Protein Alignment Ptpmeg2 and Ptpra

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_006235068.1
• Gene: Ptpra / 25167
• RGDID: 3450
• Length: 805
• Species: Rattus norvegicus
• Alignment Length: 530
• Identity: 161/530 - (30%)
• Similarity: 234/530 - (44%)
• Gaps: 110/530 - (20%)

  Fly   355 GSAAIVSTNGTE-------TEAATTAATIISAVHQLGDNNT---TVVTV------SNGVGPAGSA 403
            |:..::.|:.||       |..:|::...:|.......|.|   |.||.      .||...|.|.
  Rat    30 GTTRLIKTSTTESAKEENKTSNSTSSVISLSVTPTFSPNLTLEPTYVTTVNSSHSDNGTKRAAST 94

  Fly   404 SGGATTAA---------------SAATEPNE-NITINGLSPSHRQAANNSSSSSSSAATVANPL- 451
            ..|.||.:               .|.|||.| |.:....:|.....|.||.|......|   |:
  Rat    95 ESGGTTISPNGTYGTWLTDNQFTDARTEPWEGNSSTAATTPETFPPAGNSDSKDRRDET---PII 156

  Fly   452 -------------------------KLNTSGSADNNSTITNATTAAGAAGAAAGTTTNGGGEFWS 491
                                     |...:||..|:..::|..|.                :...
  Rat   157 AVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTE----------------DVEP 205

  Fly   492 ENPPSSASSGFSDDDSLAGQEGDPKPIDQIVQMVKQR--GRHGLIKEYADIRNRAP-EGTFLHAR 553
            ::.|..|.|..::      ::..|.|:|::.:.:.:|  ..:.|.:|..:.....| :.|...|.
  Rat   206 QSVPLLARSPSTN------RKFPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAAS 264

  Fly   554 MRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWR 618
            ...|..||||.::|.||||||.|...:|...||||||:|::||::||.:|:.|||..:|..||||
  Rat   265 KEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWR 329

  Fly   619 MIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASL------ 677
            |||||:...|||.|.:.||...||.|||  .::....:|:..|....|....||.|...
  Rat   330 MIWEQNTATIVMVTNLKERKECKCAQYW--PDQGCWTYGNVRVSVEDVTVLVDYTVRKFCIQQVG 392

  Fly   678 ELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIV 742
            ::.|.|..  |.::.:.||||||:|||.:.:.||.||:||:....|        :||     .||
  Rat   393 DVTNRKPQ--RLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQ--------YAG-----AIV 442

  Fly   743 VHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE-YAY 806
            ||||||:||||||:.:|..:..:......|:.|.|.:||:||...:|...||||.:.||:| |.|
  Rat   443 VHCSAGVGRTGTFVVIDAMLDMMHSERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLY 507

  Fly   807 SRGMLQTVDL 816
            ....|:...|
  Rat   508 GDTELEVTSL 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	109/276 (39%)
Ptpra	XP_006235068.1	PHA03255	<18..177	CDD:165513	32/149 (21%)
		R-PTPc-A-1	217..512	CDD:350469	118/317 (37%)
		R-PTPc-A-2	566..793	CDD:350471