DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg2 and ZK616.65

DIOPT Version :9

Sequence 1:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_001293838.1	Gene:	ZK616.65 / 24105295	WormBaseID:	WBGene00235383	Length:	543	Species:	Caenorhabditis elegans

Alignment Length:	430	Identity:	113/430 - (26%)
Similarity:	177/430 - (41%)	Gaps:	62/430 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   386 NNTTVVTVSNGVGPAGSASGGATTAASAATEPNENITINGLSPSHRQAANNSSSSSS---SAATV 447
            |::..::.||...|.|:.......|..........|.::|    ..:|..:.:|.:|   ...|.
Worm   146 NHSNSLSGSNEAVPPGNVKRSPQKATHPIRTTRSLIGLDG----ETEAVYSKTSKTSPDKGKVTA 206

  Fly   448 ANPLKLNTSGSADNNSTITNATTAAGAAGAAAGTTTNGGGEFWSENPPSSASSGFSDDDSLAGQE 512
            .:|....||.|.:.||:..|                              .|...:||:..  :|
Worm   207 DSPRSRRTSKSLEENSSEAN------------------------------DSISLADDEET--RE 239

  Fly   513 GDPKPIDQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLA 577
            ...|.........::.......:|::::....|...........|..||||.::.|.|.|||.|.
Worm   240 AYRKLFKDFAMSSQKMTLDDFKQEFSNLPGDPPSDLCTAFNQPVNNKKNRYLNIPCLDISRVQLK 304

  Fly   578 HEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKC 642
            .......:|||:||::.....|..||.||||..:|..|||||||:::...|||..:..|..|.||
Worm   305 VMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFTETNREKC 369

  Fly   643 GQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSA 707
            .:|:.......|:|....|.......|:..:...|.|.  ...|.|.::||.:..|||:.||.|:
Worm   370 AEYFPRNAHCCLQFDKMSVSYEDSTVNKSLVTTRLNLS--YEGETRLITHWLWKEWPDWQVPGSS 432

  Fly   708 MAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGT-A 771
            ..||..|:|:|                 .|..|.|:|||||:||:||.:.::|.:..:....| .
Worm   433 EVMLKILRKIR-----------------ARSTPPVIHCSAGVGRSGTLMAVEIALQSIHSHFTLP 480

  Fly   772 DIRGTVEKIR-SQRAYSIQMPDQYVFCHLALIEY--AYSR 808
            ||:..|..:| :.||.|:|...||:.....|:::  ||.:
Worm   481 DIKQIVSHLRVTGRAASVQTLQQYMLIWKVLLDFGVAYKQ 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	85/247 (34%)
		PTPc	559..803	CDD:238006	84/245 (34%)
ZK616.65	NP_001293838.1	PTPc	260..513	CDD:214550	87/271 (32%)
ZK616.65	NP_001293838.1	PTPc	286..513	CDD:238006	84/245 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910