Protein Alignment Ptpmeg2 and Ptpro

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_036021846.1
• Gene: Ptpro / 19277
• MGIID: 1097152
• Length: 1261
• Species: Mus musculus
• Alignment Length: 473
• Identity: 147/473 - (31%)
• Similarity: 223/473 - (47%)
• Gaps: 82/473 - (17%)

  Fly   387 NTTVVTVSNGVG--------PAGSASGGATTAASAATEPNENITINGLSPSHRQAANNSSSSSSS 443
            :.|::.|..||.        ..||...|......|.:  :..:||:.|.|:   .|.|.|.:|.|
Mouse   783 SVTLLWVEEGVADFFEVFCQQLGSGHNGKLQEPVAVS--SHVVTISSLLPA---TAYNCSVTSFS 842

  Fly   444 AATVANP--LKLNTSGSADNNSTITNATTA----------------------AGAAGAAAGTTTN 484
            ..|.:.|  :.::|..:..|.:.:..:..|                      ..|....|||..|
Mouse   843 HDTPSVPTFIAVSTMVTEVNPNVVVISVLAILSTLLIGLLLVTLVILRKKHLQMARECGAGTFVN 907

  Fly   485 GGG-EFWSENPPSSASSGFS----------DDDSLA------GQEG-------DPKPIDQIVQMV 525
            ... |...:.|.|...|.|:          .|..||      .:.|       :|..:|.....:
Mouse   908 FASLEREGKLPYSWRRSVFALLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDSYI 972

  Fly   526 KQRGRHGLIK---EYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDY 587
            |...:....|   ::.:::....:.....|.:..|..|||||::|.||.|||.|...:.:|.:||
Mouse   973 KDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADY 1037

  Fly   588 INANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEES 652
            ||||::.||.....||:||||||:|..|||:|:.:|...:|||.|:..|:.||||..||..|||
Mouse  1038 INANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSHIIVMLTQCNEKRRVKCDHYWPFTEE- 1101

  Fly   653 SLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVP--SSAMAMLNFLQ 715
            .:.:||..|..:|.|..||:  ||...|....||.::|.|:.:|:|||:|||  ::|.::|.|:.
Mouse  1102 PIAYGDITVEMVSEEEEEDW--ASRHFRINYADEAQDVMHFNYTAWPDHGVPPANAAESILQFVF 1164

  Fly   716 KVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKI 780
            .||::.|:            .:| |:::|||||:|||||||.||..:..:.|....||.|.|.::
Mouse  1165 TVRQQAAK------------SKG-PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 1216

  Fly   781 RSQRAYSIQMPDQYVFCH 798
            ||.|...:|..:||:|.|
Mouse  1217 RSYRMSMVQTEEQYIFIH 1234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	108/275 (39%)
Ptpro	XP_036021846.1	FN3	479..571	CDD:238020
		FN3	575..675	CDD:238020
		fn3	770..850	CDD:394996	18/71 (25%)
		R-PTPc-O	996..1240	CDD:350462	107/255 (42%)