Protein Alignment Ptpmeg2 and Ptprj

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_006499054.1
• Gene: Ptprj / 19271
• MGIID: 104574
• Length: 1351
• Species: Mus musculus
• Alignment Length: 817
• Identity: 211/817 - (25%)
• Similarity: 319/817 - (39%)
• Gaps: 235/817 - (28%)

  Fly   153 LYNID--PDVEPLRSELQTGKFTILPARTSSGAAIALFTANRHSPLSVSH-----TTTLQGIVYQ 210
            |||:.  |:|:.::               ....:|..:|    .|.||||     |||...|.::
Mouse   617 LYNVTIFPEVDQIQ---------------GISNSITQYT----RPSSVSHIEVNTTTTTAAIRWK 662

  Fly   211 LDSALQDSETQRAGLVFIYDMSGSKY-SNFDYDLSQKILTLLKG-GYPARLKKVLIVT------- 266
            .:.|.  |.:....::.:....||.. |||..|.|..|..|:.| .|     .|.|:|
Mouse   663 NEDAA--SASYAYSVLILKTGDGSNVTSNFTKDPSILIPELIPGVSY-----TVKILTQVGDGTT 720

  Fly   267 --APLWFKAPFKILRLFVREKLRERVFTVSV----PQLALHVPRKALP--IHLGGTLEVDHATWL 323
              .|.|        .||..|......|...|    |.|.|   :.|.|  ::.|..|.|...:|
Mouse   721 SLVPGW--------NLFCTEPEPVTSFHCEVVPKEPALVL---KWACPFGMYTGFELGVRSDSW- 773

  Fly   324 LSCRQSMTNREDELLANIVGVGGGSGSGSAAGSAAIVSTNGTETEAATTAATIISAVHQLGDNNT 388
                .:||..|:                         .|:..:||..|..|.:..:.    ..|.
Mouse   774 ----DNMTRLEN-------------------------CTSDDDTECRTEVAYLNFST----SYNI 805

  Fly   389 TVVTVSNG--VGPAGS-ASGGATTAASAATEPN--------ENITINGLSPSH------------ 430
            ::.|:|.|  ..||.: .:.|.|...:....||        ..:..:|...||
Mouse   806 SIATLSCGKMALPAQNICTTGITDPPTPDGSPNITSVSHNSVKVKFSGFEASHGPIKAYAVILTT 870

  Fly   431 RQAANNSS----------SSSSSAATVANPLKLNTSGSADNNSTITN--------ATTAAGAAG- 476
            .:||..|:          ...:|...|...:::...|.:...|.:.|        :||.....|
Mouse   871 GEAAQPSADVLKYTYEDFKRGASDTYVTYLIRIEEKGQSQGLSEVLNYEIDVGNQSTTLGYYNGR 935

  Fly   477 ---------AAAGTTT-----------NGGGEFWSENPPS------------------------- 496
                     ..||.|.           ||...:.|.:|.|
Mouse   936 LEPLGSYRACVAGFTNITYNLQNDGLINGDESYVSFSPYSEAVFLPQDPGVICGAVFGCIFGALA 1000

  Fly   497 -SASSGF---------SDDDSLAGQEGDPKPIDQI------VQMVKQR--GRHGLIKEYADIR-- 541
             :|..||         :.::.::..:..||....|      ....||:  ...|..:||.|::
Mouse  1001 ITAVGGFIFWRKKRTDAKNNEVSFSQIKPKKSKLIRVENFEAYFKKQQADSNCGFAEEYEDLKLI 1065

  Fly   542 -NRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYIST 605
             ...|:.|   |.:..|..||||.:||.||.|||.|:.:. ....||||||::.||..|..:|:|
Mouse  1066 GISLPKYT---AEIAENRGKNRYNNVLPYDISRVKLSVQT-HSTDDYINANYMPGYHSKKDFIAT 1126

  Fly   606 QGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNE 670
            |||||.|.:|||||:||::...|||.|:.:|:||.||.:|| |::::. ::||..|...|.....
Mouse  1127 QGPLPNTLKDFWRMVWEKNVYAIVMLTKCVEQGRTKCEEYW-PSKQAQ-DYGDITVAMTSEVVLP 1189

  Fly   671 DYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGH 735
            ::.:....::|::..|...:..:.||||||:|||.:...::||...||:...|:
Mouse  1190 EWTIRDFVVKNMQNSESHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQI----------- 1243

  Fly   736 PRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVF---C 797
            |...||:||||||:|||||||.:|..|.::|:..|.|:.|.|..:|..|...:|..|||||   |
Mouse  1244 PPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQC 1308

  Fly   798 HLALI--------EYAYSRGMLQTVDLAGFDEREPDS 826
            .|.:|        :..|......|:    ::..||.|
Mouse  1309 VLDIIRAQKDSKVDLIYQNTTAMTI----YENLEPVS 1341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559	40/165 (24%)
		PTPc-N9	529..799	CDD:350391	108/275 (39%)
Ptprj	XP_006499054.1	fn3	162..222	CDD:394996
		FN3	199..699	CDD:442628	25/102 (25%)
		PTP_tm	849..979	CDD:465889	22/129 (17%)
		R-PTPc-J	1083..1311	CDD:350463	99/241 (41%)