Protein Alignment Ptpmeg2 and Ptprf

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_006502927.1
• Gene: Ptprf / 19268
• MGIID: 102695
• Length: 1924
• Species: Mus musculus
• Alignment Length: 326
• Identity: 127/326 - (38%)
• Similarity: 182/326 - (55%)
• Gaps: 45/326 - (13%)

  Fly   495 PSSASSGFSDDDSLAGQEGDPKPIDQIVQMVKQ-RGRHGL--IKEYADIRNRAPEGTFLHARMRA 556
            |.|::....:..|:  ::..|.||..:...::: :...||  .:||..| :...:.|:.::....
Mouse  1330 PGSSAPSCPNISSM--RDHPPIPITDLADNIERLKANDGLKFSQEYESI-DPGQQFTWENSNSEV 1391

  Fly   557 NLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIW 621
            |..||||.:|:.||||||:|...||...|||||||::|||:::||||:||||||:|..|||||:|
Mouse  1392 NKPKNRYANVIAYDHSRVLLTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVW 1456

  Fly   622 EQHCLVIVMTTRVMERGRVKCGQYW-----------EPTEESSLEFGDYHVRTISVECNEDYMVA 675
            ||....:||.||:.|:.||||.|||           :.|...::|...|.:||.:
Mouse  1457 EQRTATVVMMTRLEEKSRVKCDQYWPVRGTETYGLIQVTLVDTVELATYTMRTFA---------- 1511

  Fly   676 SLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHP-RGP 739
               |....:.|.|.:..:||.:|||:|||.....:|.||::|:              |.:| ...
Mouse  1512 ---LHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVK--------------ACNPLDAG 1559

  Fly   740 PIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY 804
            |:|||||||:||||.||.:|..:.|::...|.||.|.|..:||||.|.:|..|||||.|.||:|.
Mouse  1560 PMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA 1624

  Fly   805 A 805
            |
Mouse  1625 A 1625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	116/283 (41%)
Ptprf	XP_006502927.1	I-set	33..124	CDD:400151
		Ig strand B	50..54	CDD:409353
		Ig strand C	63..67	CDD:409353
		Ig strand E	86..93	CDD:409353
		Ig strand F	104..109	CDD:409353
		Ig strand G	117..120	CDD:409353
		IgI_2_RPTP_IIa_LAR_like	136..232	CDD:409400
		Ig strand A	136..138	CDD:409400
		Ig strand A'	143..147	CDD:409400
		Ig strand B	150..159	CDD:409400
		Ig strand C	164..170	CDD:409400
		Ig strand C'	172..174	CDD:409400
		Ig strand D	183..187	CDD:409400
		Ig strand E	196..201	CDD:409400
		Ig strand F	210..217	CDD:409400
		Ig strand G	220..231	CDD:409400
		IgI_3_RPTP_IIa_LAR_like	241..322	CDD:409401
		Ig strand A	241..243	CDD:409401
		Ig strand A'	247..251	CDD:409401
		Ig strand B	254..262	CDD:409401
		Ig strand C	267..273	CDD:409401
		Ig strand C'	275..277	CDD:409401
		Ig strand D	280..284	CDD:409401
		Ig strand E	289..294	CDD:409401
		FN3	294..718	CDD:442628
		Ig strand F	301..308	CDD:409401
		Ig strand G	312..321	CDD:409401
		FN3	598..1065	CDD:442628
		PTP_DSP_cys	1352..1627	CDD:475123	121/302 (40%)
		R-PTP-F-2	1629..1919	CDD:350477