Protein Alignment Ptpmeg2 and Ptprd

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_036019731.1
• Gene: Ptprd / 19266
• MGIID: 97812
• Length: 1966
• Species: Mus musculus
• Alignment Length: 418
• Identity: 143/418 - (34%)
• Similarity: 211/418 - (50%)
• Gaps: 72/418 - (17%)

  Fly   427 SPSHRQAANNSSSSSSSAATVANPL---KLNTSGSADNNSTITNATTAAGAAGAAAGTTTNGGGE 488
            |.|.:.:..||....|...|  :|:   :||....|.:::::..|:.....:..::.|||.   .
Mouse  1311 SESRKSSLPNSKEVPSHHPT--DPVELRRLNFQTPALSSNSVPYASLIGSVSSLSSQTTTQ---S 1370

  Fly   489 FWSENP-PSSASSGFSDDDSLAGQEGDPKPIDQI---VQMVKQRGRHGLIKEYADIRNRAPEGTF 549
            .:..|. |..|..|.:..        .|.||.::   ::.:|........:||..| :...:.|:
Mouse  1371 IYDNNSLPRFARKGMASH--------PPIPILELADHIERLKANDNLKFSQEYESI-DPGQQFTW 1426

  Fly   550 LHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQ 614
            .|:.:..|..||||.:|:.||||||:|:..:|...|||:|||::|||:::||||:|||.||:|..
Mouse  1427 EHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFG 1491

  Fly   615 DFWRMIWEQHCLVIVMTTRVMERGRVKCGQYW-----------EPTEESSLEFGDYHVRTISVEC 668
            |||||||||....:||.|::.||.||||.|||           :.|...::|...|.|||.::..
Mouse  1492 DFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYK 1556

  Fly   669 NEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWA 733
            |             .:.|.|.|..:|||:|||:|||......|.||::|:.             .
Mouse  1557 N-------------GSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKT-------------C 1595

  Fly   734 GHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCH 798
            ..|...|:|||||||:||||.||.:|..:.|::...|.||.|.|..:|:||.|.:|..|||:|.|
Mouse  1596 NPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIH 1660

  Fly   799 LALIE--------------YAYSRGMLQ 812
            .||:|              |||.:.:.|
Mouse  1661 DALLEAVTCGNTEVPARNLYAYIQKLTQ 1688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	113/280 (40%)
Ptprd	XP_036019731.1	I-set	31..123	CDD:400151
		Ig strand B	48..52	CDD:409390
		Ig strand C	61..65	CDD:409390
		Ig strand E	85..92	CDD:409390
		Ig strand F	103..108	CDD:409390
		Ig strand G	116..119	CDD:409390
		IgI_2_RPTP_IIa_LAR_like	135..234	CDD:409400
		Ig strand A	135..137	CDD:409400
		Ig strand A'	142..146	CDD:409400
		Ig strand B	149..158	CDD:409400
		Ig strand C	163..169	CDD:409400
		Ig strand C'	171..173	CDD:409400
		Ig strand D	182..186	CDD:409400
		Ig strand E	198..203	CDD:409400
		Ig strand F	212..219	CDD:409400
		Ig strand G	222..233	CDD:409400
		IgI_3_RPTP_IIa_LAR_like	247..328	CDD:409401
		Ig strand A	247..249	CDD:409401
		Ig strand A'	253..257	CDD:409401
		Ig strand B	260..268	CDD:409401
		Ig strand C	273..279	CDD:409401
		Ig strand C'	281..283	CDD:409401
		Ig strand D	286..290	CDD:409401
		Ig strand E	295..300	CDD:409401
		Ig strand F	307..314	CDD:409401
		FN3	312..>744	CDD:442628
		Ig strand G	318..327	CDD:409401
		fn3	721..820	CDD:394996
		FN3	<797..1135	CDD:442628
		FN3	930..1021	CDD:238020
		R-PTPc-D-1	1388..1671	CDD:350472	121/317 (38%)
		R-PTP-D-2	1672..1963	CDD:350476	4/17 (24%)