Protein Alignment Ptpmeg2 and Ptpra

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_036015592.1
• Gene: Ptpra / 19262
• MGIID: 97808
• Length: 838
• Species: Mus musculus
• Alignment Length: 572
• Identity: 168/572 - (29%)
• Similarity: 246/572 - (43%)
• Gaps: 136/572 - (23%)

  Fly   349 GSG---SAAGSAAIVSTNGTETEAATTAATIISAVHQLGDNNTTVVTVSNGVGPAGSASGGATTA 410
            |||   .:|.:|..||.:...|....|:.|.::.......|:|:.| :|..|.|        |.:
Mouse    11 GSGLIHVSANNATTVSPSLGTTRLIKTSTTELAKEENKTSNSTSSV-ISLSVAP--------TFS 66

  Fly   411 ASAATEPNENITINGLSPSHRQAANNSSSSSSSAATVANPLKLNTSGSADNNST--IT-----NA 468
            .:...||....|:|.   ||.......::|:.|..|..:|   |.|...:|..|  ||     |:
Mouse    67 PNLTLEPTYVTTVNS---SHSDNGTRRAASTESGGTTISP---NGSWLIENQFTDAITEPWEGNS 125

  Fly   469 TTAAGA------AGAAAGTTTN--------------GGGEFWSENPPSSASSGFSD--DDS---- 507
            :|||..      ||.|.|..::              .....|:.:|...::|...|  |::
Mouse   126 STAATTPETFPPAGMARGLPSHQEPSHSYIACHRMTAFSSAWAHSPNVISNSDSKDRRDETPIIA 190

  Fly   508 ---------------------------LAGQEGD------------------------------- 514
                                       .||...:
Mouse   191 VMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYP 255

  Fly   515 PKPIDQIVQMVKQR--GRHGLIKEYADIRNRAP-EGTFLHARMRANLTKNRYTDVLCYDHSRVVL 576
            |.|:|::.:.:.:|  ..:.|.:|..:.....| :.|...|....|..||||.::|.||||||.|
Mouse   256 PLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHL 320

  Fly   577 AHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVK 641
            ...:|...||||||:|::||::||.:|:.|||..:|..|||||||||:...|||.|.:.||...|
Mouse   321 TPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECK 385

  Fly   642 CGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASL------ELRNIKTDEIRNVSHWQFTSWPD 700
            |.|||  .::....:|:..|....|....||.|...      ::.|.|..  |.::.:.||||||
Mouse   386 CAQYW--PDQGCWTYGNVRVSVEDVTVLVDYTVRKFCIQQVGDVTNRKPQ--RLITQFHFTSWPD 446

  Fly   701 YGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRL 765
            :|||.:.:.||.||:||:....|        :||     .||||||||:||||||:.:|..:..:
Mouse   447 FGVPFTPIGMLKFLKKVKACNPQ--------YAG-----AIVVHCSAGVGRTGTFVVIDAMLDMM 498

  Fly   766 EDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE-YAYSRGMLQTVDL 816
            ......|:.|.|.:||:||...:|...||||.:.||:| |.|....|:...|
Mouse   499 HSERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSL 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	109/276 (39%)
Ptpra	XP_036015592.1	R-PTPc-A-1	250..545	CDD:350469	118/311 (38%)
		R-PTPc-A-2	599..826	CDD:350471