DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ptpmeg2 and Ptpn5

DIOPT Version :10

Sequence 1:NP_572576.1 Gene:Ptpmeg2 / 31907 FlyBaseID:FBgn0028341 Length:827 Species:Drosophila melanogaster
Sequence 2:NP_038671.2 Gene:Ptpn5 / 19259 MGIID:97807 Length:541 Species:Mus musculus


Alignment Length:247 Identity:100/247 - (40%)
Similarity:135/247 - (54%) Gaps:18/247 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   560 KNRYTDVLCYDHSRVVLAHEDGDEP-SDYINANFVDGYK-QKNAYISTQGPLPKTSQDFWRMIWE 622
            ||||..:|...||||.|...|.::| |.|||||::.||. ::..||:||||:..|..|||||:|:
Mouse   301 KNRYKTILPNPHSRVRLTSPDPEDPLSSYINANYIRGYSGEEKVYIATQGPIVSTVADFWRMVWQ 365

  Fly   623 QHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEI 687
            :...:|||.|.:.|... ||.:||  .||..:..| ..:....|...|||.:..:.||  :..|.
Mouse   366 ERTPIIVMITNIEEMNE-KCTEYW--PEEQVVHDG-VEITVQKVIHTEDYRLRLISLR--RGTEE 424

  Fly   688 RNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRT 752
            |::.|:.||||||...|..|..:|:.:::|.|...|  :|        |...||:||||||||||
Mouse   425 RSLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQ--EG--------PHCSPIIVHCSAGIGRT 479

  Fly   753 GTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY 804
            |.||...||..:|...|..||..|..::|..|...||..:||.|.|.|:..|
Mouse   480 GCFIATSICCQQLRREGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHAMSLY 531

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ptpmeg2NP_572576.1 CRAL_TRIO_N <114..144 CDD:215024
SEC14 170..314 CDD:469559
PTPc-N9 529..799 CDD:350391 97/240 (40%)
Ptpn5NP_038671.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..55
PTPc-N5 274..531 CDD:350461 99/245 (40%)
Blue background indicates that the domain is not in the aligned region.

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