Protein Alignment Ptpmeg2 and Ptpn18

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_035336.2
• Gene: Ptpn18 / 19253
• MGIID: 108410
• Length: 453
• Species: Mus musculus
• Alignment Length: 301
• Identity: 112/301 - (37%)
• Similarity: 166/301 - (55%)
• Gaps: 39/301 - (12%)

  Fly   530 RHG--LIKEYADIRNRA----PEG---TFLHARMRANLTKNRYTDVLCYDHSRVVLA--HEDGDE 583
            |.|  |.:|::||:.|:    .||   |...:|: .|..||||.||:.||.:||:|:  .|:|.
Mouse    21 REGAILAREFSDIKARSVAWKSEGVCSTKAGSRL-GNTNKNRYKDVVAYDETRVILSLLQEEGH- 83

  Fly   584 PSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEP 648
             .|||||||:.|.....|||:||||||.|..||||::||....||:|..:..|.||.||.:|| .
Mouse    84 -GDYINANFIRGIDGSQAYIATQGPLPHTLLDFWRLVWEFGVKVILMACQETENGRRKCERYW-A 146

  Fly   649 TEESSLEFGDYHVRTISVE--CNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAML 711
            .|:..|:.|.:.: |::.|  .|.|..:.:|::...|  |.|:|...|:.||||:|||||:..:|
Mouse   147 REQEPLKAGPFCI-TLTKETTLNADITLRTLQVTFQK--EFRSVHQLQYMSWPDHGVPSSSDHIL 208

  Fly   712 NFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTA----D 772
            ..::     :|:.:||||.        .|:.||||||.||||....:|. :.:|....|.    .
Mouse   209 TMVE-----EARCLQGLGP--------GPLCVHCSAGCGRTGVLCAVDY-VRQLLLTQTIPPNFS 259

  Fly   773 IRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGMLQT 813
            :...|.::|.||..::|..:||.|.:..:.: .:||.:..|
Mouse   260 LFQVVLEMRKQRPAAVQTEEQYRFLYHTVAQ-LFSRTLQDT 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	109/285 (38%)
Ptpn18	NP_035336.2	PTP_DSP_cys	27..292	CDD:475123	106/286 (37%)
		PRK12323	<331..>452	CDD:481241
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	384..453