Protein Alignment Ptpmeg2 and Ptpn1

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_035331.3
• Gene: Ptpn1 / 19246
• MGIID: 97805
• Length: 432
• Species: Mus musculus
• Alignment Length: 275
• Identity: 116/275 - (42%)
• Similarity: 156/275 - (56%)
• Gaps: 22/275 - (8%)

  Fly   537 YADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNA 601
            |.|||:.|.:.....|::..|..:|||.||..:||||:.|..||    :|||||:.:...:.:.:
Mouse    20 YQDIRHEASDFPCKVAKLPKNKNRNRYRDVSPFDHSRIKLHQED----NDYINASLIKMEEAQRS 80

  Fly   602 YISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVR--TI 664
            ||.||||||.|...||.|:|||....:||..|:||:|.:||.|||...||..:.|.|..::  .|
Mouse    81 YILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRIMEKGSLKCAQYWPQQEEKEMVFDDTGLKLTLI 145

  Fly   665 SVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREK-QAQLVQGL 728
            |.:....|.|..|||.|:.|.|.|.:.|:.:|:|||:|||.|..:.||||.||||. ...|..|
Mouse   146 SEDVKSYYTVRQLELENLTTKETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSLEHG- 209

  Fly   729 GDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICI---SRLEDVGTADIRGTVEKIRSQRAYSIQM 790
                       ||||||||||||:|||...|.|:   .:.:|..:.||:..:.::|..|...||.
Mouse   210 -----------PIVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRRFRMGLIQT 263

  Fly   791 PDQYVFCHLALIEYA 805
            .||..|.:||:||.|
Mouse   264 ADQLRFSYLAVIEGA 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	111/267 (42%)
Ptpn1	NP_035331.3	PTPc-N1	16..292	CDD:350456	116/275 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..322
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	335..399