DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg2 and T27A3.5

DIOPT Version :9

Sequence 1:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_491761.3	Gene:	T27A3.5 / 188965	WormBaseID:	WBGene00020841	Length:	355	Species:	Caenorhabditis elegans

Alignment Length:	327	Identity:	115/327 - (35%)
Similarity:	166/327 - (50%)	Gaps:	48/327 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   509 AGQEGD-PKPI-DQIVQMVKQRGRHGLIKEYADIR------NRAPEGTFLHARMRANLTKNRYTD 565
            |.|.|| .:|| ...|:...|.|...|..|:.:::      |:...|...|..      ||||.|
Worm    48 AAQYGDVNEPILRDFVKATIQTGVKQLSTEFLNLKMETQPCNKPKTGHEGHPE------KNRYKD 106

  Fly   566 VLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVM 630
            |.|.|.:||||...: |.|||||:||:|. ....|.:|.||||..||..||:|:||::....:||
Worm   107 VYCIDDTRVVLKWPE-DSPSDYIHANWVK-INGANKFICTQGPTEKTVDDFYRLIWQEKAPCVVM 169

  Fly   631 TTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISV-----ECNEDYMVASLELRNIKTDEIRNV 690
            ...:||.|:.||.|||..|.:..:...|..: |:.:     |..::.::..:.:.:.|... .|.
Worm   170 LCNIMECGKKKCEQYWPETADGQMILMDGKL-TVKIAEPAKEVEQNILLMKITVIDDKGTS-HNF 232

  Fly   691 SHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTF 755
            .|||:.:|||.|||...||:...|  :|.|.|.                ||||||||||||||:.
Worm   233 EHWQWKAWPDRGVPELPMAVFRLL--IRLKTAS----------------PIVVHCSAGIGRTGSI 279

  Fly   756 ITLDICISRL---EDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGMLQTVDLA 817
            :.|:|.:.:.   |.|...||   |::||:||..|:|...||:|.|..|:..|.:| .:.:.:|:
Worm   280 VGLEIALVKFCAGEKVVLKDI---VKEIRNQRHGSVQTDAQYLFMHRVLLALAENR-KITSPELS 340

  Fly   818 GF 819
            .|
Worm   341 AF 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	97/253 (38%)
		PTPc	559..803	CDD:238006	97/251 (39%)
T27A3.5	NP_491761.3	PTPc	73..326	CDD:214550	101/283 (36%)
T27A3.5	NP_491761.3	PTPc	100..326	CDD:238006	96/256 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910