DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg2 and T04F3.3

DIOPT Version :9

Sequence 1:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_505965.2	Gene:	T04F3.3 / 188063	WormBaseID:	WBGene00011438	Length:	364	Species:	Caenorhabditis elegans

Alignment Length:	337	Identity:	77/337 - (22%)
Similarity:	154/337 - (45%)	Gaps:	48/337 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   516 KPIDQIVQMVKQRGRHGLIKEYADI------RNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRV 574
            :|:|..::::   ....:.||::..      |.|..:..|.|..:      |::.::..|:.:||
Worm    49 RPLDIFIKLL---STSSVGKEFSHFSSLPLSRLRTVDAFFDHPEL------NKFGEIQVYEQTRV 104

  Fly   575 VLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVM-ERG 638
            ...|..|   .:|:|::::|||::...:|....|:.::...|||.:::::.|::|....:: |:|
Worm   105 RAVHRQG---HNYLNSSWIDGYRETRKFIVAPSPMSESVAQFWRCVFDRNSLIVVTLCELLDEKG 166

  Fly   639 R----VKCGQYWEP--TEESSLEFGDYH-VRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFT 696
            :    ||.|   ||  .::.::|..:.. ||..:..       :.|::.....:..:.|....::
Worm   167 KPFVPVKIG---EPLVIDDMTIELDNIRKVRPATYS-------SVLKISEKGVESHKTVILLTYS 221

  Fly   697 SWPDYGVPSSAMAMLNFLQKVREKQAQL-VQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDI 760
            .|...|.|.....:|:.|..:...:..| .|||........:..|:.:.|..|..|:.|.:.|||
Worm   222 GWGKLGYPQKPSDILDLLADMNHMRTILRKQGLEKKIFDDSQRTPMTLVCFDGFSRSCTLVALDI 286

  Fly   761 CISRL---EDVGT--ADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGMLQTVDLA--- 817
            ...||   .::||  .||..|:.::|..|..:....:|:||..::::|||....::...||.
Worm   287 LCQRLTASHEIGTPFVDILDTIARLRMLRGAACMKAEQFVFLSMSVLEYAIRHHLVNVEDLGKIS 351

  Fly   818 --GFDER-EPDS 826
              ||..| .|:|
Worm   352 LNGFIIRNNPES 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	59/259 (23%)
		PTPc	559..803	CDD:238006	59/257 (23%)
T04F3.3	NP_505965.2	Y_phosphatase	87..334	CDD:278528	60/265 (23%)
T04F3.3	NP_505965.2	PTPc	89..334	CDD:238006	59/263 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910