Protein Alignment Ptpmeg2 and M04G7.2

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_499934.1
• Gene: M04G7.2 / 187449
• WormBaseID: WBGene00019773
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 495
• Identity: 133/495 - (26%)
• Similarity: 217/495 - (43%)
• Gaps: 74/495 - (14%)

  Fly   362 TNGTETEAATTAATIISAVHQLGDNNTTVVTVSNGVGPAGSASGGATTAASAATEPNE------N 420
            |......||::.:...:..|:.......|..|.|.: |...:....:|:....:|.|.      :
 Worm    59 TKPVPVPAASSNSKGSNEKHKRKSVQQVVKKVVNHI-PFSPSKQPKSTSTPPVSEGNRKRLAMAD 122

  Fly   421 ITINGL-----------SPSHRQAA----NNSSSSSSSAATVANPLKLNTSGSADNNSTITNATT 470
            ::||.|           .|:.|:|.    :||.|.|:.|....|   :.||....::..|....:
 Worm   123 VSINQLESEMDSFVKKIEPNERRATQYIHSNSLSRSNEAVPPGN---VKTSQQKADHHLIRTTRS 184

  Fly   471 AAGAAG------AAAGTTTNGGGEFWSENPPS---------SASSGFSDDDSLAGQEGDPKPIDQ 520
            ..|..|      :.|...:...|:..:::|.|         ::|...:|..|||..|...:...:
 Worm   185 LIGLDGETEAVYSKATKASPDKGKLTADSPSSRRTSKSLEENSSETTNDSISLADDEETREAYRK 249

  Fly   521 IVQ---MVKQRGRHGLIK-EYADIRNRAPEG---TFLHARMRANLTKNRYTDVLCYDHSRVVLAH 578
            :.:   |..|:......| |::::....|..   .|.|.   .|..||||:::.|.|.|||.|..
 Worm   250 LFKDFAMSSQKMTLDDFKQEFSNLPGDPPSDLCTVFNHP---VNNKKNRYSNIPCLDISRVQLKF 311

  Fly   579 EDGDEPS-DYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKC 642
            :..::.| |||:||::.....|..||.||||..:|..|||||||:::...|||..:.:|..|.||
 Worm   312 KMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKC 376

  Fly   643 GQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSA 707
            .:|:.......|:|..:.|.......|:..:...|.|.  ...|.|.::||.:..|||:.||.|:
 Worm   377 AEYFPRNAHCCLQFDKFSVNYEDSTVNKSLVTTRLNLS--YEGETRLITHWLWKEWPDWQVPESS 439

  Fly   708 MAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGT-A 771
            ..||..|:|:|                 .|..|.|:|||||:||:||.:.::|.:..:....| .
 Worm   440 EVMLKILRKIR-----------------ARSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLP 487

  Fly   772 DIRGTVEKIR-SQRAYSIQMPDQYVFCHLALIEY--AYSR 808
            ||:..|..:| :.||.|:|...||:.....|:::  ||.:
 Worm   488 DIKQIVSHLRVTGRAASVQTLQQYMLIWKVLLDFGVAYKQ 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	90/276 (33%)
M04G7.2	NP_499934.1	PTZ00108	<9..242	CDD:240271	37/186 (20%)
		PTPc	266..520	CDD:214550	91/275 (33%)