DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ptpmeg2 and F35C11.2

DIOPT Version :9

Sequence 1:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_495736.1	Gene:	F35C11.2 / 185271	WormBaseID:	WBGene00009401	Length:	397	Species:	Caenorhabditis elegans

Alignment Length:	400	Identity:	91/400 - (22%)
Similarity:	168/400 - (42%)	Gaps:	94/400 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   473 GAAGAAAGT---TTNGGGEFWSENPPSSASSGFSDDDSLAG--QEGDPKPIDQIVQMVKQRGRHG 532
            |:....|||   ||..||| .:|......:...:.:::...  .|| |:.::|:         |.
Worm    22 GSIRQLAGTESQTTQTGGE-TAEGKEEEVNKNVTPEEAFKAVTVEG-PELLNQM---------HT 75

  Fly   533 LIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYK 597
            ....|.:..::     ||:     |:..||...:.|:|||||.||.:||.:  |:.||::||||.
Worm    76 SAMTYPNTYDK-----FLN-----NMDMNRIPHLYCFDHSRVELAPQDGKD--DFYNASWVDGYS 128

  Fly   598 QKNAYISTQGPL-PKTSQDFWRMIWEQHCLVIVMTTRVMERGRVK-------------------- 641
            :|:|||..|.|. ..|...||||:.|:...:|::...:.|:.:.|
Worm   129 KKSAYIFAQAPFNDHTEYVFWRMVSERKPSMILVFGDIDEKQKRKAPYDISDRGFEKSFLHEFGA 193

  Fly   642 ------------CGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSH-- 692
                        |.::| |.:.|..:|     ..:|::.::|:....::..|:...| :...|
Worm   194 KSLEECELKAKICRKFW-PEKGSKKDF-----PALSIQASDDHSETHMKTFNLTVTE-KKQDHQT 251

  Fly   693 --WQFTSW------PDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGI 749
              ..|..|      |:|.:...|...|.:::.  .|:..:..|            ||::.|:.|:
Worm   252 VLMHFYEWADASKLPEYMLDMRASIKLQYIRS--SKKTGVCIG------------PIMLVCATGV 302

  Fly   750 GRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGMLQTV 814
            .:...:.|:||.:||:.:......:.|:..|:.||....:....|......|:::|.:.|::.
Worm   303 EKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFAVTTGVVH-- 365

  Fly   815 DLAGFDEREP 824
            |.|..::.:|
Worm   366 DAAIGEKPKP 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	68/288 (24%)
		PTPc	559..803	CDD:238006	67/286 (23%)
F35C11.2	NP_495736.1	PTPc	83..356	CDD:214550	70/305 (23%)
F35C11.2	NP_495736.1	PTPc	94..344	CDD:304379	65/272 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910