DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg2 and C15H7.3

DIOPT Version :9

Sequence 1:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_499135.1	Gene:	C15H7.3 / 182639	WormBaseID:	WBGene00007610	Length:	398	Species:	Caenorhabditis elegans

Alignment Length:	365	Identity:	68/365 - (18%)
Similarity:	120/365 - (32%)	Gaps:	93/365 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   486 GGEFWSENPPSSASSGFSDDDSLAGQEGDPKPIDQIVQMVKQRGRHGLIKEYADIRNRAP----- 545
            |..|.|......:|||.|:..:....:.|.|..|:..:..::|      ||......:.|
Worm    53 GNGFTSRETIQPSSSGQSEGTTRMDDQKDEKKDDKKEEKKEER------KEEKKEEVKEPWSEEE 111

  Fly   546 ----------------EGTFLHA-----------RMRANLTKNRYTDVLCYDHSRVVLAHEDGDE 583
                            .|||...           ..:.|:.|.|..|....:...|.|.    :.
Worm   112 PAKRMVANGFFTTTNVGGTFKQTDNFKTPMDSCPSFKNNMHKIRAPDCPIPEEKLVKLT----NG 172

  Fly   584 PSDYINANFVDGYKQKNAYISTQGP----LPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQ 644
            |..:|.|..:.........|.||.|    .|..: ||||||.::....:|:....:
Worm   173 PESFICAAKITVPDFNRTMILTQVPDLSSAPDIA-DFWRMIHQESIASVVIAVMPL--------- 227

  Fly   645 YWEPTEESSLEF--GDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSA 707
              |.|.:..|..  |.|..            ...:.:.|.|.:....::.:....:|| |..:|.
Worm   228 --EVTLQQILPLLSGTYST------------YGKMFVNNKKVESAVGMTEYCLEIFPD-GCSNSL 277

  Fly   708 MAMLNFLQKVREKQA-----------QLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDIC 761
            :..:..|...|:|:.           :.|..:.|.         .|:....|.||.||.:||...
Worm   278 LTTVYHLHNWRQKRGLEVVTDLVATMEKVMKVNDN---------TVLMSMNGTGRAGTMLTLFTA 333

  Fly   762 ISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLAL 801
            :.:::.....:.:.|:..:|::|...:...||:...|.::
Worm   334 MLQVQKGKEVNAKETLASLRAERCGIVDNIDQFGTVHRSM 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	51/262 (19%)
		PTPc	559..803	CDD:238006	50/260 (19%)
C15H7.3	NP_499135.1	PTPc	131..374	CDD:214550	52/281 (19%)
C15H7.3	NP_499135.1	PTPc	148..374	CDD:304379	51/264 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910