DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg2 and Y116A8C.33

DIOPT Version :9

Sequence 1:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_503035.1	Gene:	Y116A8C.33 / 178488	WormBaseID:	WBGene00013809	Length:	712	Species:	Caenorhabditis elegans

Alignment Length:	187	Identity:	39/187 - (20%)
Similarity:	61/187 - (32%)	Gaps:	53/187 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   418 NENITINGLSPSHRQAANNSSSSSSSAATVANPLKLNTSGSA----------------------D 460
            ||.|.|:|:..|:|. ::.|:..|.:...:.:.||..:.||.                      |
Worm    63 NETIAIDGILNSYRN-SDISNFKSENILKLIDDLKATSMGSEQEVLKVESQLIKYNTFIDELKFD 126

  Fly   461 NNSTITNA-----TTAAGAAGAAAGTTTNGG----------GEF--WSE---NPPSSASSGFSDD 505
            .|:...:.     .|....|.....:|.||.          ||.  |.|   |.|.:.:......
Worm   127 GNTLELHGKYKFFDTLRDLAIDVKDSTDNGHRFIVDMLEYIGEMLQWLEEGLNVPFNITERTMSP 191

  Fly   506 DSLAGQEGDPKPIDQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNR 562
            ..|..:.|.       :.:.....||   .||.:..|::.|.||...|....|..:|
Worm   192 QFLLEKLGS-------IMLKVSSVRH---VEYLEGMNKSIESTFKPLREMFKLMNDR 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	2/6 (33%)
		PTPc	559..803	CDD:238006	1/4 (25%)
Y116A8C.33	NP_503035.1	WSN	36..96	CDD:391742	9/33 (27%)
		235kDa-fam	<54..576	CDD:130673	39/187 (21%)
		BAR	110..>247	CDD:386243	26/139 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_2QR81
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900