DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg2 and K07F5.8

DIOPT Version :9

Sequence 1:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_501766.1	Gene:	K07F5.8 / 177833	WormBaseID:	WBGene00010636	Length:	284	Species:	Caenorhabditis elegans

Alignment Length:	271	Identity:	90/271 - (33%)
Similarity:	133/271 - (49%)	Gaps:	46/271 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   560 KNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQH 624
            ||||.||.|.|::||.|.   |..|.:||:||:|........:|.||.||.||..|||.|..:..
Worm    21 KNRYKDVGCLDNNRVKLG---GAWPHEYIHANYVSTPTNPKRFICTQAPLEKTCADFWFMCLQDR 82

  Fly   625 CLVIVMTTRVMERGRVKCGQYWEPTEES--SLEFGDYHVR-TISVECNE-----DYMVAS----- 676
            ...|.|.....|:|..||.:|. |||::  ::.|.:...: |:..|.::     |...|.
Worm    83 VETIFMLCNYKEKGAKKCHEYL-PTEDNKDTMSFKEKGQKVTVKFESSKAIKFRDNSAAKVTKTV 146

  Fly   677 LELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPI 741
            |.:.....|::: |:|:.:..|||.|||::..|:|..|:|.|..:.                 ||
Worm   147 LTVEGAGCDKLK-VNHYHWIDWPDRGVPTADNAILELLEKARVSKG-----------------PI 193

  Fly   742 VVHCSAGIGRTGTFITLDICISRL------EDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLA 800
            .|||||||||||:.:.|:..:.:|      ||...     .::|||.||..|:|...||:|.|..
Worm   194 AVHCSAGIGRTGSVVMLEYVMDQLLAGQIIEDTDK-----IIQKIREQRNNSVQTDHQYLFVHQV 253

  Fly   801 LIEYAYSRGML 811
            ::.:...||:|
Worm   254 MMNFFEKRGLL 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	87/261 (33%)
		PTPc	559..803	CDD:238006	87/261 (33%)
K07F5.8	NP_501766.1	Y_phosphatase	19..256	CDD:278528	87/261 (33%)
K07F5.8	NP_501766.1	PTPc	20..256	CDD:238006	87/261 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910