DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg2 and C17H12.3

DIOPT Version :9

Sequence 1:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_001379692.1	Gene:	C17H12.3 / 177443	WormBaseID:	WBGene00015929	Length:	374	Species:	Caenorhabditis elegans

Alignment Length:	356	Identity:	111/356 - (31%)
Similarity:	161/356 - (45%)	Gaps:	54/356 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   476 GAAAGTTTNGGGEFWSENPPSSASSGFS-DDDSLAGQEGDPKP--------------IDQIVQMV 525
            |....|.|.      :|..|.....|.: .|:.:|.....|.|              ::|.||..
Worm    12 GKKGNTKTE------NERGPKKDKGGKTIVDEDIATTITAPPPNASQQPQLVQAHPIVEQFVQRA 70

  Fly   526 KQRGRHGLIKEYADI-RNRAPEGT--FLHARMRANL--TKNRYTDVLCYDHSRVVLAHEDGDEPS 585
            ...|...|..|:..: :...|:.|  ..:|...||:  |||||.||.|.|.:.|::|....  ||
Worm    71 LDYGVEKLRDEFRQMAKYTRPDMTQNAFNANQSANINETKNRYADVPCQDQNIVLVAKPPA--PS 133

  Fly   586 DYINANFVD-GYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPT 649
            ||::||||. .......:|.|||||..|..|||.||.:|....|||..:.:|.|:.||.|||...
Worm   134 DYVHANFVGCPMVPDKRFICTQGPLDHTVDDFWWMIVQQKVEQIVMLCKTIETGKYKCAQYWPLA 198

  Fly   650 EESSLEF-GDYHVRTIS----VECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMA 709
            .....|. |...|..:|    ::.:.:..:.:|::.  ..|:..:|.|..::.|||.|||...:.
Worm   199 MGEKKEVKGGIVVENVSGTKPMDRDAEIQITTLQVS--FGDQKMSVRHLHWSDWPDRGVPPCKLT 261

  Fly   710 MLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRL-EDVGTADI 773
            .|..|..||..:.                 |||||||||||||||.:.::..:.|: |:.....:
Worm   262 SLELLSAVRGSRV-----------------PIVVHCSAGIGRTGTIVAIEYILERIAENKQCPPM 309

  Fly   774 RGTVEKIRSQRAYSIQMPDQYVFCHLALIEY 804
            ...|:.:|.|||||||...||::.|..::.|
Worm   310 PDLVKSLRDQRAYSIQTDMQYLYIHRVMLNY 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	90/254 (35%)
		PTPc	559..803	CDD:238006	89/250 (36%)
C17H12.3	NP_001379692.1	PTPc	77..339	CDD:214550	96/282 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910