DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg2 and C01G5.4

DIOPT Version :9

Sequence 1:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_500995.1	Gene:	C01G5.4 / 177414	WormBaseID:	WBGene00015306	Length:	1079	Species:	Caenorhabditis elegans

Alignment Length:	477	Identity:	84/477 - (17%)
Similarity:	164/477 - (34%)	Gaps:	129/477 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   387 NTTVVTVSNGVGPAGSASGGATTAAS-----AATEPNENITINGLSPSHRQAANNSS-----SSS 441
            ||.....|:.:|...|.|.|:..|||     ...|.:.:.:::..:|..:.|.:..|     |:|
Worm    41 NTGAQDQSSDIGQGRSVSSGSPDAASQDYQLIGQESSSDHSVSLATPLSKHAPDRRSSFLKRSAS 105

  Fly   442 SSAATVANP-LKLNTSGSADNNSTITNATTAAGAAGAAAGTTTNGGGEFWSENPPSSASSGFSDD 505
            ...:..::| ..::.|.....:....||||:.....|.  :|||..|.....:..:..::|.:
Worm   106 GHESPFSHPNADVSPSSPQQLHLAFANATTSTNVTNAK--STTNFDGYLKHISVIAHVANGIT-- 166

  Fly   506 DSLAGQEGDPKPIDQIVQMVKQRGRHGLIK-EYADIRNRAPEGTFLHARMRANLTKNRYTDVLCY 569
             ..||...:..|||.:|..:     .||.. |.:||..:..:......:::
Worm   167 -LQAGLMNEKIPIDAVVGEL-----FGLRSIELSDIFYKLDKIAAWTRKLK-------------- 211

  Fly   570 DHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRV 634
                        |.|:|...:..:|..:.|                                  :
Worm   212 ------------DIPNDLKASTELDELESK----------------------------------I 230

  Fly   635 MERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIK--TDEIRNVSHWQFT- 696
            :|..:::...........|.:..||.....:|:.|       ||..|.|  :|..|.:|....|
Worm   231 LELDQIRMESDGVQNVLESSKLTDYFATVKNVKNN-------LEKYNFKLFSDANREISTVLITL 288

  Fly   697 -----------SWPDY-GVPSSA---MAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPI--VV- 743
                       .|..| .:||..   ||.:..::|:.:|..:  :..|:...|.....|:  |:
Worm   289 EKILSSATAKELWNKYRSLPSQCKKMMAAIEAVKKIDKKSIE--KEYGEMAVGATTFKPLEQVID 351

  Fly   744 -------HCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLAL 801
                   :.:.|...|...:..:  :.::.::...|..|..::|       :::.::....|..:
Worm   352 LMVRRERYSNKGANNTRNMVEAN--LEKVNEINANDASGDFKQI-------LELVNRAEQDHSKM 407

  Fly   802 IEYAYSRGMLQTVDLAGFDERE 823
            ....:|||:|....:|| |.|:
Worm   408 HTIGFSRGILDLKHVAG-DARD 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	37/273 (14%)
		PTPc	559..803	CDD:238006	37/271 (14%)
C01G5.4	NP_500995.1	WSN	146..213	CDD:197734	15/100 (15%)
C01G5.4	NP_500995.1	PRK03918	<199..>402	CDD:235175	36/280 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_2QR81
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900