DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg2 and Y48G9A.9

DIOPT Version :9

Sequence 1:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_001022893.1	Gene:	Y48G9A.9 / 175343	WormBaseID:	WBGene00021702	Length:	361	Species:	Caenorhabditis elegans

Alignment Length:	325	Identity:	104/325 - (32%)
Similarity:	158/325 - (48%)	Gaps:	46/325 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   518 IDQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGD 582
            ::..:...::.|..||.|:|..: :...:.:......:.|:.||||:||:|.|.:||.|. .|..
Worm    57 LNNFIIATEKLGIEGLAKQYRKL-DAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLT-IDKS 119

  Fly   583 EPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWE 647
            ...|||:||:|.....:|.:|.|||||..|..||||||:::....|:|..:.||.||.||..||
Worm   120 RYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYW- 183

  Fly   648 PTEESSLEFGDYHVRTISVECNEDYMVASLELR----NIKTD-------EIR-NVSHWQFTSWPD 700
            |:...:..:|...|..:. |.::::.:.:|.:.    |:..|       |:| |:..|  .:|||
Worm   184 PSLGVTETYGCIRVTNMG-ESSDEFEICNLAVTFVPDNVPVDEQPANLKELRVNLIKW--PNWPD 245

  Fly   701 YGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRL 765
            .|||.             ||...:.|.|    ....|..|.||||||||||||..:.|:...::|
Worm   246 RGVPD-------------EKCHTVPQRL----LAQVRHGPCVVHCSAGIGRTGCVVALEFAYNKL 293

  Fly   766 EDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRG-------MLQTVD--LAGFDE 821
            :.....|....:.::|.|||..||...||::.|..:|  |::||       .|...|  |..:||
Worm   294 DRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMI--AFARGETDVSEKALAAADAFLKSYDE 356

Fly 822 821
Worm 357 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	90/257 (35%)
		PTPc	559..803	CDD:238006	89/255 (35%)
Y48G9A.9	NP_001022893.1	PTPc	71..330	CDD:214550	94/281 (33%)
Y48G9A.9	NP_001022893.1	PTPc	97..330	CDD:238006	89/254 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910