Protein Alignment Ptpmeg2 and K09F6.3

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_001342012.1
• Gene: K09F6.3 / 173583
• WormBaseID: WBGene00019586
• Length: 1391
• Species: Caenorhabditis elegans
• Alignment Length: 900
• Identity: 171/900 - (19%)
• Similarity: 292/900 - (32%)
• Gaps: 356/900 - (39%)

  Fly   130 RKFDIPRAVSLYEQHEQIRLKEYLYNIDPDVEPLRS---ELQTGKFTILPARTSSGAAIALFTAN 191
            ||.|:...      .:.|.:...|:|:...::.|::   ||....|:|
 Worm   579 RKMDVQPI------RDGIDVVNDLFNVSNQLDELKTKLRELNDPNFSI----------------- 620

  Fly   192 RHSPLS--VSHTTTL----QGIVYQLDSALQDSETQRAGLVFIYDMSGSKYSNFDYDL---SQKI 247
            ..:|||  ..||||:    :|::...|.....|:         :|:........|.::   .:|.
 Worm   621 AETPLSNPSLHTTTIGLSVRGVIRMKDEIDHRSD---------FDVVIENAEMVDQEMKNTGKKA 676

  Fly   248 LTLLKGGYPARLKKVLIVTAPLWFKAPFKILRLFV----REKLRERVFTVSVPQLA--LHVPRKA 306
            :.:::.|  :||||:         |:..:..:..:    ..::|.     |.|.||  .|:.:.|
 Worm   677 INMVEFG--SRLKKL---------KSELEGWKSNITVGGAHRIRR-----STPSLADYAHIFQNA 725

  Fly   307 LPIHLGGTLEVDHATWLLSCRQSMTNREDELLANIVGVGGGSGSGSAAGS--------AAIVSTN 363
            |.:  ||.                   :|:|...:..|.....:|..|.:        |::.|.|
 Worm   726 LKV--GGV-------------------DDDLKKLMDAVKDFEKTGKDAATKVKLKEVIASLNSLN 769

  Fly   364 --GTETEAATTAATII----SAVHQLGDNNTTVVTV------SNGVGPAGSASGGATTAASAATE 416
              |.:..:..|..|.|    ||:.....:|..::|.      |:|....|..|.|    .|...:
 Worm   770 SIGLQLSSFATPFTAIGQSFSALDAFFVSNGKIITTPAPIVSSSGASQEGQKSAG----GSMTLQ 830

  Fly   417 PNENITINGLSPSHRQAANNSSSSSSSAATVANPLKLNTS-------GSADNNSTITNATTAAGA 474
            |::.:                     |..|...|:..:|:       |.   ...:.:|...|..
 Worm   831 PSQTV---------------------SVTTTEEPMDESTNLMIFIGIGC---GIVLVSALIVAVV 871

  Fly   475 AGAAAGTTTNGGGEFWSENPPSSASSGFSDDD--------------SLAGQEG----------DP 515
            .             |:..|.       .::||              .||.||.          :.
 Worm   872 C-------------FYKRNK-------IANDDMEQGTKIEKEKIARELAAQEAQNIEAEKKKKEI 916

  Fly   516 KPIDQIVQMVKQRGRHGLIKEYA--------------------DIRN------RAPEG------- 547
            |.::..|...||:|..  |||.|                    |||:      .|.||
 Worm   917 KDLEAKVDYEKQKGEK--IKEEAEKEIQDHRKKVEDDKLPKFYDIRSPTIEDATALEGDKGATNN 979

  Fly   548 ---------TFLHARMR-ANLTKN-------------RYTDVLCYDHSRVVLAHEDGDE------ 583
                     .|..:.:| |||..|             ||:||||...:|:::     ||
 Worm   980 GKLPLKAMYQFCKSILRIANLAPNNAIVESEKYSEQDRYSDVLCGMDNRILI-----DEDVCRRC 1039

  Fly   584 --PSDYINANFVDGYKQKNAYISTQGPLPKTS------------------------------QDF 616
              ...|||||::: ....|..|.||.|:.:|.                              ..|
 Worm  1040 YFKDQYINANYLE-LPNGNRMILTQAPMSRTEHFKPEKDKKRKNLYSLSDEEEEISYLVQTVDKF 1103

  Fly   617 WRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRN 681
            ::.|.:....|:.|.....|.|..||..|:...::...:|.:.:|.|.:|:    :..|.:.||.
 Worm  1104 YQTIVQTGTEVVAMLCDFNEEGVEKCSSYFPLEKDGKQKFHNVNVCTTNVQ----HPSADVVLRT 1164

  Fly   682 I-------KTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGP 739
            :       :..:...|.|:.:..|.:...|.....:||..:..|..::
 Worm  1165 LVITSYLGEKKKTHTVKHYSYKGWIEKNAPELPREILNIFRVARNSKS----------------- 1212

  Fly   740 PIVVHCSAGIGRTGTFITLDI----CISRLEDVGTA--DIRGTVEKIRSQRAYSIQMPDQYVFCH 798
             :|||||.||||:..|:..:.    .|..|:...|.  |....:.::|..|..:|..|.|..|..
 Worm  1213 -LVVHCSNGIGRSAAFVFAEFVYQKMIRSLDTTSTVNLDFLSLLTELRHSRPRAIHTPMQLAFSI 1276

  Fly   799 LALIE---------------------YAYSRGML-----------QTVDLAGFDE 821
            :.:::                     |.::|.|:           :|||:| .||
 Worm  1277 MMVLDFVMNNFPKGEMEAKYQEIRKSYLHARQMMHKDLEFDGSDGKTVDIA-LDE 1330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	3/13 (23%)
		SEC14	170..314	CDD:469559	30/158 (19%)
		PTPc-N9	529..799	CDD:350391	80/376 (21%)
K09F6.3	NP_001342012.1	WSN	56..124	CDD:197734
		PTPc	992..1281	CDD:214550	68/316 (22%)