DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg2 and F55H12.5

DIOPT Version :9

Sequence 1:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_492395.2	Gene:	F55H12.5 / 172700	WormBaseID:	WBGene00010136	Length:	287	Species:	Caenorhabditis elegans

Alignment Length:	286	Identity:	70/286 - (24%)
Similarity:	116/286 - (40%)	Gaps:	75/286 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   532 GLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPS-DYINANFVDG 595
            |:.:.|.:....:|  ||.: ..::...||...:|..||.:||::       |. ||.:|::|||
Worm    55 GVAEFYKETYLESP--TFFN-YFKSPKDKNFSENVWLYDATRVIV-------PGVDYYHASWVDG 109

  Fly   596 YKQKNAYISTQGPL-PKTSQDFWRMIWEQHC----LVIV--------MTTRVMERGRVKCGQYWE 647
            .| .|.||..|.|. ...::||::::  :|.    |::.        ..|...|:|..|
Worm   110 LK-PNQYILAQAPRDASAAKDFFKLL--EHVKAEGLIVAEGADEFSSAITAKFEKGTGK------ 165

  Fly   648 PTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLN 712
                     .|: |.|..::.|      .|.|:.||           |..|.:   |.||:.:.:
Worm   166 ---------NDF-VSTAVIKEN------GLHLKAIK-----------FCRWAE---PLSAIEIND 200

  Fly   713 FLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTV 777
            .|:|.|:            :.|.|...|:|:.|..|..::|....:|....||...|.|....|:
Worm   201 MLEKSRK------------YLGCPLKGPLVIVCKDGAAKSGLVAFIDTEADRLMKHGKAKHTDTI 253

  Fly   778 EKIRSQRAYSIQMPDQYVFCHLALIE 803
            ::||..|:.:....|.|.....:|||
Worm   254 KQIRFMRSNTFDTFDSYDLGINSLIE 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	63/259 (24%)
		PTPc	559..803	CDD:238006	63/257 (25%)
F55H12.5	NP_492395.2	PTPc	74..270	CDD:214550	61/253 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910