DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg2 and C55B7.3

DIOPT Version :9

Sequence 1:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_001367695.1	Gene:	C55B7.3 / 172359	WormBaseID:	WBGene00016942	Length:	346	Species:	Caenorhabditis elegans

Alignment Length:	342	Identity:	107/342 - (31%)
Similarity:	162/342 - (47%)	Gaps:	49/342 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   491 SENPPSSASSGFSDDDSLAGQEGDPKPIDQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMR 555
            :|:..||..|...|:.:|..::...|.|.:.||...::...||..|:..:| |..:...:.|...
Worm    14 TESANSSTKSSVLDEPTLVERKQQKKQILKFVQRTLEKMPQGLRAEFVGMR-RFNDFEKMKAFKE 77

  Fly   556 A-NLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRM 619
            | ...||||.||.|.|::||.|   :|..|.:||:||:|........:|.||.||.||..|||.|
Worm    78 AQEAGKNRYKDVGCLDNNRVKL---EGPWPHEYIHANYVATPTNPKRFICTQAPLEKTCADFWYM 139

  Fly   620 IWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNED--YMVASLELRNI 682
            .::.....|.|...::|:|..||.:|:...:...::| :...:.|||:|...  |...|....|:
Worm   140 CYQDKVEYIFMLCNLLEKGARKCFEYFPSKKGDVMDF-EEGGQKISVKCESSVTYSFRSDAKANV 203

  Fly   683 KTDEI---------RNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRG 738
            ...||         |..:|:.:..|||.|||::.||:|..|:..|                 |..
Worm   204 TATEIVIEGPGEKTRKTTHYHWNDWPDRGVPAADMAVLELLENAR-----------------PSK 251

  Fly   739 PPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTV--------EKIRSQRAYSIQMPDQYV 795
            .||||||||||||||:.:.|:..:.:|       :.|.:        .|||.||..|||...||:
Worm   252 GPIVVHCSAGIGRTGSVVMLEYIMDQL-------LAGQIIDDGEKILVKIREQRNNSIQTDAQYL 309

  Fly   796 FCHLALIEYAYSRGMLQ 812
            |.|..::.|...:.:::
Worm   310 FVHQVILNYFRKKKLME 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	89/264 (34%)
		PTPc	559..803	CDD:238006	89/262 (34%)
C55B7.3	NP_001367695.1	Y_phosphatase	83..317	CDD:395053	89/261 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910