DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg2 and F55F8.7

DIOPT Version :9

Sequence 1:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_491657.2	Gene:	F55F8.7 / 172228	WormBaseID:	WBGene00018895	Length:	491	Species:	Caenorhabditis elegans

Alignment Length:	503	Identity:	127/503 - (25%)
Similarity:	206/503 - (40%)	Gaps:	130/503 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   383 LGDNNTT--VVTVSNGVGPAGSASGGATTAASAATEPNENITINGLSPSHRQAANNSSSSSSSAA 445
            :.|.|.|  :|||||..  |..|||.|..:.:              |..:::..|:.:.:.....
Worm     1 MSDCNWTNPLVTVSNTA--ALLASGYALWSCA--------------SKKNKKDINSETKTLDKRP 49

  Fly   446 TVANPLKLNTSGSADNNSTITNATTAAGAAGAAAGTTTNGGGEFWSENPPSSASSGFSDDDSL-- 508
            ..|..:|...:.:::...|       |.|....|....|...|...|...       |:||.|
Worm    50 QTAELVKDEKNSNSEEKKT-------ASANEVPAQKKLNSKEEVKKEKKK-------SEDDLLDV 100

  Fly   509 ---AGQEGDPKPIDQIVQMVKQRGRHGLIK-----------------------EYADIRNRAPE- 546
               ..:|.|.|.:|      |:.|...|.|                       |..|..|..|.
Worm   101 KKTVSKEDDKKKVD------KKDGSKKLSKKKLKEEKKEKSKKVNKEKKISKTESDDEDNEQPPE 159

  Fly   547 --------GTFLHARMR--------------------------ANLTKNRYTDVLCYDHSRVVLA 577
                    ..|..|:|:                          ||...|||.||.|.:.:||||.
Worm   160 PGSDPRKIWAFKAAKMKCQAISKLHQDKIKGYMPPNCTYTAYEANPDLNRYADVRCIEETRVVLK 224

  Fly   578 HEDGDEPSDYINANF--VDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRV 640
            :.|    .|||:|::  :.| |.::.||:||||||:|..|||.||:::....::|...:.|.|..
Worm   225 NHD----RDYIHASWMRMPG-KDQSTYITTQGPLPETLSDFWHMIYQEKIAYVLMLCTLFEGGVE 284

  Fly   641 KCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASL--ELRNIKTDEIRN----VSHWQFTSWP 699
            ||..|:.......::||.|.: |:: ||.|:.:..::  .|..|.|::..:    ::|.|...||
Worm   285 KCALYYPEKLGEVVKFGKYEI-TLT-ECKEEAIAGTILNSLTVINTEDATSEPLYMNHVQVPWWP 347

  Fly   700 DYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISR 764
            |...|..|..|:...:.|::.              :|:..||.||||||:|||.||:.:|....|
Worm   348 DQLAPEDARPMIELYKWVKKV--------------NPKEKPICVHCSAGVGRTATFVGIDYATIR 398

  Fly   765 LEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGMLQ 812
            :.:....::...|.::|:.|..::|...|::|.::.|:||....|:::
Worm   399 IMENPNIEMLDIVREMRAMRFQAVQSHMQFLFLYVVLMEYFIGEGVVE 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	80/253 (32%)
		PTPc	559..803	CDD:238006	79/251 (31%)
F55F8.7	NP_491657.2	PTPc	193..437	CDD:214550	81/264 (31%)
F55F8.7	NP_491657.2	PTPc	206..437	CDD:238006	79/251 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910