DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg2 and F47B3.7

DIOPT Version :9

Sequence 1:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_491276.1	Gene:	F47B3.7 / 171983	WormBaseID:	WBGene00018531	Length:	374	Species:	Caenorhabditis elegans

Alignment Length:	302	Identity:	101/302 - (33%)
Similarity:	165/302 - (54%)	Gaps:	45/302 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   522 VQMVKQRGRHGLIK-------EYADIRNR---APEGTFLHARMRANLTKNRYTDVLCYDHSRVVL 576
            |.:|:....|.|.|       |::::.|:   .|...|     ::|..||||||:.|.:.:||:|
Worm    50 VSIVRPWVHHTLNKGVSKLRDEFSEVANKNPNVPVDAF-----KSNPEKNRYTDIKCIEKTRVIL 109

  Fly   577 AHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVK 641
            . .|| ..||||:||:|....:...:|.||||...|..|||.|:.:.:...|:|..:|:|..|||
Worm   110 T-TDG-ASSDYIHANYVGISIKPKKFICTQGPKDSTIYDFWAMVIQDNVESIIMLCKVIELARVK 172

  Fly   642 CGQYWEPTE-ESSLEFGDYHVRTI------SVECNEDYM-VASLELRNIKTDEIRNVSHWQFTSW 698
            |.|||...| :::......|..||      ::..::|:: |.:|||  :...:.|:::|:|:|:|
Worm   173 CEQYWPAVEGQTNTYVSKGHTITINNLGVGTLSPDDDFINVTNLEL--VWAGKTRSITHYQWTNW 235

  Fly   699 PDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICIS 763
            ||:|.|...|..:|.::.|..          ||       .|:|||||||:||:||.:.:.:.:.
Worm   236 PDHGAPPINMGAINLIEAVNY----------DT-------NPVVVHCSAGVGRSGTIVGISLIMD 283

  Fly   764 R-LEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY 804
            : ::.:...|::..||:||:||.|:||...||::.|..|:||
Worm   284 KMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEY 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	90/254 (35%)
		PTPc	559..803	CDD:238006	89/252 (35%)
F47B3.7	NP_491276.1	Y_phosphatase	90..324	CDD:278528	90/254 (35%)
F47B3.7	NP_491276.1	PTPc	92..324	CDD:238006	89/252 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910