Protein Alignment Ptpmeg2 and Y48G1C.5

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_490668.4
• Gene: Y48G1C.5 / 171595
• WormBaseID: WBGene00021678
• Length: 1161
• Species: Caenorhabditis elegans
• Alignment Length: 934
• Identity: 170/934 - (18%)
• Similarity: 293/934 - (31%)
• Gaps: 323/934 - (34%)

  Fly   133 DIPRAVSLYEQH------------------------EQIRLKEY---LYNIDPDVEPLRSELQTG 170
            ||.|.:...|:|                        :.:|.|:|   |.|...|:..|.|:|.|.
 Worm   253 DINRGLRKLEEHMASIRNAFPNQESKIHLQTIESIGQSLRTKKYTVGLPNGAIDIGALNSQLATD 317

  Fly   171 KFTILPARTSSGAAI-------------------ALFTANRHSPLSVSHTT----TLQGIVYQLD 212
            .:    ||.::...|                   .|...:|.|.:|....|    .:|.:...:|
 Worm   318 AW----ARETTDHMIFLRELETIWLLGEEVRNVERLLRKDRFSTISQLFNTIERLDIQSLNVLVD 378

  Fly   213 SALQDSETQRAGLVFIYDMSG----SKY-SNFDYDLSQ------KILTLL---KGGYPARLKKVL 263
            .|...::..::.|....|.:.    ||. ||.|.:|.|      .::..|   |.|:    .:||
 Worm   379 EAKVIAQCAKSTLTTAPDFTNLEELSKIASNIDTELEQSKSILKSVMNQLVESKSGH----AEVL 439

  Fly   264 IV----------TAPLWFKAPFKILRLFVREKLRERVFTVSVPQLALHVPRKALPIHLGGTLEVD 318
            .|          ||...|....|:..|.:.........|...|.|...:.::|:........::.
 Worm   440 TVCKDMNNSNWTTAEPCFNGVKKMTGLSLTMSRMTANATFLNPNLLKTLEKRAIEKINDSRSDIA 504

  Fly   319 HATWLLSCRQSMTNRE-DELLANIVGVGGGSGSGS-----AAGSAAIVSTNGTETEAATTAATII 377
            ....:|||.||  |:| |::..|:..:........     .|...|::|.:...: ...:.|...
 Worm   505 QFLDVLSCLQS--NKELDKIQKNLSDLNSFRADQKFPPIVTAVEDALISVSSLNS-GLKSLALYF 566

  Fly   378 SAVHQLGDNNTT----VVTVSNGVGPAGSASGGATTAASAATEPNENITINGLSPSHRQAANNSS 438
            |...:...:.|:    ....:|.:|||      |...|.......|...:: :..:|.|....
 Worm   567 SKRRKFASDKTSQFPNAAEHTNSIGPA------AQEIARLEDVLRERANVD-IIKNHAQIVQR-- 622

  Fly   439 SSSSSAATVANPLKLNTSGSADNNSTITNATTAAGAAGAAAGTTTNGGGEFWSENPPSSASSGFS 503
            ..::|.||:|...|       ||...:    .|.||:........:.    |......|.|:.|.
 Worm   623 ELAASGATLAQDDK-------DNLEKL----VALGASLDVMFVQLDA----WKSGIKKSDSTKFV 672

  Fly   504 DDD------------SLAGQEGDPKPIDQIVQMVKQRGRH----------------GLIKEYADI 540
            |..            :|.|..|..|.::::|::||..|..                ||  |::..
 Worm   673 DYGYVFTEAKKVDWANLGGLMGLEKSLEKLVELVKDVGNKKSLGEVQDALKSLDDGGL--EFSSF 735

  Fly   541 RNRAPEGTFLHARMR---ANLTKNRYTDVL--------------CYDHSR-VVLA---------- 577
            :||..|.....|.:.   :||.|...|.:|              ...|.: |:||
 Worm   736 QNRLDEPKKALAALDLFFSNLFKPLPTAILPPPDLGNSEKNGPPPQTHGQYVILALIVIVIICAI 800

  Fly   578 ---------------HEDGDE---PSDYIN---------ANFVDGY---------KQKNA----- 601
                           .|:.::   |:..|:         :||:..:         :::|.
 Worm   801 IAYFCLTPNGYKILDSEEKEKLYPPNQMISRVDVNETRFSNFLKTFNTQISDFVTRKRNCTSVFE 865

  Fly   602 ---------------YISTQG------------------------------------------PL 609
                           :...||                                          |:
 Worm   866 NVPNNLEITGDDFAQFCGLQGGNHCQCDPVSYESSKKNGQGESSHVVELDNGLKFVLMPAPQLPV 930

  Fly   610 PKTSQD------FWRMIWEQHCLVIVMTTRVME------RGRVKCGQYWEPTE-ESSLEFGDYHV 661
            .|.|.|      ||..:.......|||.....|      ..:|.|.:|: ||| :..|...|
 Worm   931 DKKSSDILAIAAFWESVKLNKPSTIVMLCDFAEIDHFIGANKVNCDRYF-PTELDEKLILAD--- 991

  Fly   662 RTISVECNEDYMVASLELRNI-------KTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVRE 719
              :::.|.:......|:.|.:       :|.|   |:|:|:|.||::..|..|..:...|:.|.:
 Worm   992 --LTITCTKSISKPLLKTRQLLLTFGKKRTQE---VTHYQYTGWPEHMGPKDAEEIRYLLKLVTD 1051

  Fly   720 KQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRL--EDVGTADIRGTVEKIRS 782
            .:.                 |:.|.|:.|.||:..|:.::.....:  .:.|..:.|..:|:.||
 Worm  1052 SER-----------------PVFVVCNTGGGRSAAFVLIESLFQAINTSETGEINYRSLIEQTRS 1099

  Fly   783 QRAYSIQMPDQYVFCHLALIEYAY 806
            :|..:...|....|.....:...|
 Worm  1100 KRKCAAPDPIYLAFAFYTTLTLFY 1123

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	4/10 (40%)
		SEC14	170..314	CDD:469559	35/190 (18%)
		PTPc-N9	529..799	CDD:350391	73/433 (17%)
Y48G1C.5	NP_490668.4	WSN	47..111	CDD:426657
		PTPc	<940..1101	CDD:214550	41/186 (22%)