Protein Alignment Ptpmeg2 and ptprfa

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_068077727.1
• Gene: ptprfa / 140819
• ZFINID: ZDB-GENE-020107-2
• Length: 1910
• Species: Danio rerio
• Alignment Length: 327
• Identity: 127/327 - (38%)
• Similarity: 179/327 - (54%)
• Gaps: 41/327 - (12%)

  Fly   493 NPPSSASSGFSDDDSLAGQEGDPKPIDQIVQMVKQ-RGRHGL--IKEYADIRNRAPEGTFLHARM 554
            |..:..||.|:...:...:|..|..:..:...::: |....|  .:||..: :...:.|:.::.:
Zfish  1312 NYQTQGSSAFNCPSTSRMREHPPVSVCALADHIERLRANDSLRFSQEYESV-DPGQQFTWENSNL 1375

  Fly   555 RANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRM 619
            ..|..||||.:|:.||||||||...||...|||||.|::|||:::||||:||||||:|..|||||
Zfish  1376 EVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINGNYIDGYRKQNAYIATQGPLPETLSDFWRM 1440

  Fly   620 IWEQHCLVIVMTTRVMERGRVKCGQYW--EPTEE---------SSLEFGDYHVRTISVECNEDYM 673
            :|||....|||.||:.|:.||||.|||  ..||.         .::|...|.|||.::..|
Zfish  1441 VWEQRTSTIVMMTRLEEKSRVKCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKN---- 1501

  Fly   674 VASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRG 738
                     .:.|.|.|..:||.:|||:|||.....:|.||::|:.             ...|..
Zfish  1502 ---------GSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKA-------------CNPPDA 1544

  Fly   739 PPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE 803
            .|:|||||||:||||.||.:|..:.|::...:.||.|.|..:||||.|.:|..|||:|.|.||:|
Zfish  1545 GPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLE 1609

  Fly   804 YA 805
            .|
Zfish  1610 AA 1611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	115/282 (41%)
ptprfa	XP_068077727.1	Ig strand F	210..217	CDD:409400
		Ig strand G	220..231	CDD:409400
		IgI_3_RPTP_IIa_LAR_like	241..322	CDD:409401
		Ig strand A	241..243	CDD:409401
		Ig strand A'	247..251	CDD:409401
		Ig strand B	254..262	CDD:409401
		Ig strand C	267..273	CDD:409401
		Ig strand C'	275..277	CDD:409401
		Ig strand D	280..284	CDD:409401
		Ig strand E	289..294	CDD:409401
		FN3	299..735	CDD:442628
		Ig strand F	301..308	CDD:409401
		Ig strand G	312..321	CDD:409401
		FN3	716..812	CDD:238020
		FN3	817..898	CDD:238020
		FN3	915..1003	CDD:238020
		FN3	1013..1082	CDD:238020
		PTP_DSP_cys	1340..1613	CDD:475123	121/299 (40%)
		PTP_DSP_cys	1615..1905	CDD:475123
		I-set	33..124	CDD:400151
		Ig strand B	50..54	CDD:409353
		Ig strand C	63..67	CDD:409353
		Ig strand E	86..93	CDD:409353
		Ig strand F	104..109	CDD:409353
		Ig strand G	117..120	CDD:409353
		IgI_2_RPTP_IIa_LAR_like	136..232	CDD:409400
		Ig strand A	136..138	CDD:409400
		Ig strand A'	143..147	CDD:409400
		Ig strand B	150..159	CDD:409400
		Ig strand C	164..170	CDD:409400
		Ig strand C'	172..174	CDD:409400
		Ig strand D	183..187	CDD:409400
		Ig strand E	196..201	CDD:409400