Protein Alignment Ptpmeg2 and Ptpmeg2

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_322055.5
• Gene: Ptpmeg2 / 1282054
• VectorBaseID: AGAMI1_004321
• Length: 718
• Species: Anopheles gambiae
• Alignment Length: 814
• Identity: 489/814 - (60%)
• Similarity: 568/814 - (69%)
• Gaps: 126/814 - (15%)

  Fly    32 LFLCIAKAVKQFIDLCNNLGANCSTTTATSPSTSSSSASSTQNLIAVVPPQLQQLQVQLPAPGGG 96
            :.|...||||||||..|                   |:|:..|..||.|
Mosquito    13 ILLWALKAVKQFIDRIN-------------------SSSNDPNRKAVTP---------------- 42

  Fly    97 GGAGAGGGGGGGGGAAPVRRHISHTTAVKFLYARKFDIPRAVSLYEQHEQIRLKEYLYNIDPDVE 161
                                    ..|.:||.|||:||.||::||||||.||.:|.||..||..|
Mosquito    43 ------------------------AIATRFLLARKYDITRAMALYEQHELIRQREGLYGFDPQTE 83

  Fly   162 PLRSELQTGKFTILPARTSSGAAIALFTANRHSPLSVSHTTTLQGIVYQLDSALQDSETQRAGLV 226
            |||:||:||||||||.|.:|||||||||||.|.|::|:|.|||||:|||||.|||.||||:||||
Mosquito    84 PLRTELETGKFTILPGRDASGAAIALFTANLHYPMTVTHKTTLQGVVYQLDVALQSSETQKAGLV 148

  Fly   227 FIYDMSGSKYSNFDYDLSQKILTLLKGGYPARLKKVLIVTAPLWFKAPFKILRLFVREKLRERVF 291
            ||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   149 FIYDMSTSKYSNFDYDLSQKILTLLKGGYPARLKKVLIVTAPLWFKAPFKILRLFVREKLRERVF 213

  Fly   292 TVSVPQLALHVPRKALPIHLGGTLEVDHATWLLSCRQSMTNREDELLANIVGVGGGSGSGSAAGS 356
            |||:|||:|||||::||:.|||||||||::|||.|.:||||||||
Mosquito   214 TVSIPQLSLHVPRESLPVRLGGTLEVDHSSWLLHCYKSMTNREDE-------------------- 258

  Fly   357 AAIVSTNGTETEAATTAATIISAVHQLGDNNTTVVTVSNGVGPA-GSASGGATTAASAATEPNEN 420
              |::|.|.:.:...|:           .:|:|.:....|..|. |||...|..|.:...:.:.:
Mosquito   259 --IIATAGQQQQQPQTS-----------QSNSTDLNGVIGASPVMGSAGIAAIAAGTGTLDTHHS 310

  Fly   421 IT------------INGLSPSHRQAANNSSSSSSSAATVANPLKLNTSGSADNNSTITNA----- 468
            :|            :|  |.:||.:..|       .|.|.:.|.:...    :|..:..|
Mosquito   311 LTGVVGSELVDVEFVN--SHNHRVSPEN-------GAEVEDHLNVEDI----SNIAVVGANQHLP 362

  Fly   469 TTAAGAAGAAAGTTTNGGGEFWSENPPSSASSGFSDDDSLAGQEGDPKPIDQIVQMVKQRGRHGL 533
            ...||..|.....||:   |.|:|||||||||||||||||||.|||||.|:||||||::||:.||
Mosquito   363 ANHAGHVGHQNHHTTS---ELWTENPPSSASSGFSDDDSLAGAEGDPKTIEQIVQMVRERGKMGL 424

  Fly   534 IKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQ 598
            |:||.:|:.|||:|||.||::|.||.|||||||||||||||||:.|:.|..:|||||||||||||
Mosquito   425 IREYTEIKARAPDGTFTHAKLRNNLAKNRYTDVLCYDHSRVVLSQEEDDPATDYINANFVDGYKQ 489

  Fly   599 KNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRT 663
            |||||||||||||||.|||||:||||||:||||||||||||.||||||||||....|:|.:.:||
Mosquito   490 KNAYISTQGPLPKTSYDFWRMVWEQHCLLIVMTTRVMERGRAKCGQYWEPTEGGLAEYGSFRLRT 554

  Fly   664 ISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGL 728
            :|:|.||||.|..||:|||||||:|.||||||||||||||||||.|||||||:.|||||::|:.|
Mosquito   555 MSIETNEDYTVVELEIRNIKTDEVRCVSHWQFTSWPDYGVPSSAKAMLNFLQRAREKQAEMVRAL 619

  Fly   729 GDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQ 793
            ||.||||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||||
Mosquito   620 GDLWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIKGTVEKIRSQRAYSIQMPDQ 684

  Fly   794 YVFCHLALIEYAYSRGMLQTVDLAGFDEREPDSE 827
            ||||||||||||.||.|||:|||:.||:|:.:|:
Mosquito   685 YVFCHLALIEYALSRSMLQSVDLSEFDDRDEESD 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	13/29 (45%)
		SEC14	170..314	CDD:469559	123/143 (86%)
		PTPc-N9	529..799	CDD:350391	218/269 (81%)
Ptpmeg2	XP_322055.5	None