Protein Alignment Ptpmeg2 and Ptp69D

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_061508307.1
• Gene: Ptp69D / 1273859
• VectorBaseID: AGAMI1_008430
• Length: 1471
• Species: Anopheles gambiae
• Alignment Length: 776
• Identity: 175/776 - (22%)
• Similarity: 290/776 - (37%)
• Gaps: 211/776 - (27%)

  Fly   198 VSHTTTLQGIV-YQLDSALQDSETQRAGLVFIYDMSGSKYSNFDYDLSQKILTLLKGGYPARLKK 261
            :|:...|.|:. |:.:..:..|           |:.|.|..|.:.|.............|.....
Mosquito   480 MSYQAILSGVANYRSEFGMMKS-----------DIWGPKIKNINPDSYSTAYATEYDNVPPNTNY 533

  Fly   262 VLIVTAPLWFKAPFKILRLFVREKLRERVFTVSVPQLALHVPRKALPIHLG----GTLEVDHATW 322
            .:.|||....|.|..:...           |.::|        ...|.:||    |.|..|...|
Mosquito   534 TVNVTAHTRTKRPGVVASA-----------TCTMP--------ATTPDNLGRISWGKLRTDQDDW 579

  Fly   323 L--------------LSCRQ------------SMTNREDELLANIVGVGGGSGSGSAAGSAAIVS 361
            :              :.|.:            |:...|:.|:.:...|...:.:......|.:.:
Mosquito   580 IFKLFLPRLSERNGPICCYKVYLTRIHIHHNGSLPAPENALITSYADVHSINNTHGGTYLAEVFA 644

  Fly   362 TNGTETEAATTAATIISAVHQLGD--NNTTV------------VTVSNGVGPAGSASGGA----- 407
            ...::||..            |||  |:..|            |.|.....||.:....|
Mosquito   645 GMSSQTEVF------------LGDGKNSPAVGLCPQCLQMRHRVQVEAERAPATTELPAARDDLP 697

  Fly   408 ----TTAASAATEPNENITINGLSPSHRQAANNSSSSSSSAATVANPLKLNTSGSADNNSTITN- 467
                .|||..|...||.:   .|....:.::|:....:.........|:....|:.|..|..|.
Mosquito   698 AADDVTAAPGARTGNEAV---ALEDERKASSNHEKRDTGKYYESLTRLETVFDGALDPTSNYTGF 759

  Fly   468 ----ATTAAGAAGAAAGTTTNGGGEFWSENPPSSASSGFSDDDSLA------------------- 509
                ..|.:|..|....:|.:   |::.|....:...|..|.:.|:
Mosquito   760 LEVVVKTDSGNDGRDYLSTFS---EYFQEMNAGAPMEGDVDGNDLSYILNIVIQVLLALIAVVVI 821

  Fly   510 ----------------GQEGDPKPI-DQIVQMVKQRGR--------------------------- 530
                            .|||:...: |.:.:.:...||
Mosquito   822 VLMVLCFLHKHVSNNIAQEGEAISLGDSLRRALCNGGRGVNVHHRHLLGSSSAKPPVLPPISKDD 886

  Fly   531 -------------HGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGD 582
                         :|...|:..:.::..:.|..::.|:.|:.||||.|:..||.:||.|...:|.
Mosquito   887 LPKAYNDKHKDSDYGFQHEFELLPDKFADRTTKNSDMKENMPKNRYPDIKAYDQTRVKLTPLNGL 951

  Fly   583 EPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWE 647
            ..|||||||||.|||::..:|..|||:..|..||||||||||..:|||.|.:.|..:.||.:||.
Mosquito   952 AGSDYINANFVIGYKERKKFICAQGPMDATINDFWRMIWEQHLEIIVMLTNLEEYNKTKCAKYWP 1016

  Fly   648 PTEESSLEFGDYHVRTISVECNEDYMVASLEL--RNIKTDE--IRNVSHWQFTSWPDYGVPSSAM 708
            .:...|:::|:..:...|:....||::.:|::  |:..:.|  .|.:|.:.:.:|.|:..|....
Mosquito  1017 ESTNDSIQYGELLITFQSLTYYADYIIRTLKVTKRSASSGEETSREISQYHYLAWKDFMAPEHPQ 1081

  Fly   709 AMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADI 773
            .:..|:.::..:.: |.:|            ||:||||||:||||||:.||..:.:|::.|...|
Mosquito  1082 GITKFINRINSEYS-LQRG------------PILVHCSAGVGRTGTFVALDTLMQQLQEEGQVFI 1133

  Fly   774 RGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAY-------SRGMLQTVDLAGFDEREPDSE 827
            ..|:..:|.||.:.:|...||:|.:.||.|.||       .:.:..|::..    ::|.||
Mosquito  1134 FNTICDMRYQRNFLVQSLKQYIFLYRALAELAYFGDTEIDQKSLASTIEAL----KQPSSE 1190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559	21/120 (18%)
		PTPc-N9	529..799	CDD:350391	97/313 (31%)
Ptp69D	XP_061508307.1	None