Protein Alignment Ptpmeg2 and Ptpre

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_038964618.1
• Gene: Ptpre / 114767
• RGDID: 620771
• Length: 719
• Species: Rattus norvegicus
• Alignment Length: 303
• Identity: 118/303 - (38%)
• Similarity: 162/303 - (53%)
• Gaps: 35/303 - (11%)

  Fly   515 PKPIDQIVQMVKQRGRHGLIKEYADIRNRAP----EGTFLHARMRANLTKNRYTDVLCYDHSRVV 575
            |.|::.:.:.::.|.... .|.:.:..|..|    :|||..|....|..||||.::|..||.||:
  Rat   133 PIPVEHLEEEIRVRSADD-CKRFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHCRVI 196

  Fly   576 LAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRV 640
            |:..||...||||||:::||||:||.:|:.|||..:|..|||||:|||....|||.|.:.||...
  Rat   197 LSQLDGIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQRSATIVMLTNLKERKEE 261

  Fly   641 KCGQYWEPTEESSLEFGDYHVRTISVECNE------DYMVASLELRNIKTDEI---RNVSHWQFT 696
            ||.|||  .::....:|:..|      |.|      ||.:....:.....|..   |.||...||
  Rat   262 KCYQYW--PDQGCWTYGNIRV------CVEDCVVLVDYTIRKFCIHPQLPDSCKAPRLVSQLHFT 318

  Fly   697 SWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDIC 761
            ||||:|||.:.:.||.||:||:.        |..:.||     |||||||||:|||||||.:|..
  Rat   319 SWPDFGVPFTPIGMLKFLKKVKT--------LNPSHAG-----PIVVHCSAGVGRTGTFIVIDAM 370

  Fly   762 ISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY 804
            :..:......|:...|.:||:||...:|...||.|.:.||:||
  Rat   371 MDMIHSEQKVDVFEFVSRIRNQRPQMVQTDVQYTFIYQALLEY 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:469559
		PTPc-N9	529..799	CDD:350391	111/282 (39%)
Ptpre	XP_038964618.1	R-PTPc-E-1	184..412	CDD:350468	102/248 (41%)
		PTP_DSP_cys	499..708	CDD:475123