Protein Alignment Ptpmeg2 and ptprjb.1

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_073799246.1
• Gene: ptprjb.1 / 101883510
• ZFINID: ZDB-GENE-090304-1
• Length: 4416
• Species: Danio rerio
• Alignment Length: 951
• Identity: 212/951 - (22%)
• Similarity: 317/951 - (33%)
• Gaps: 317/951 - (33%)

  Fly    55 STTTATSPSTSSSSASSTQNLIAVVPPQLQQLQVQLPAPGGGGGAGAGGGGGGGGGAAPVRRHIS 119
            ||.|:|.|.||:|::||| |.....|   ..|......|.............|...:.|.....:
Zfish  3560 STQTSTFPITSASTSSST-NETHTTP---TTLSTSASTPITSHTTATDSSSTGSQTSTPSTTVTT 3620

  Fly   120 HTTAVKFLYARKFDIPRAVSLYEQHEQIRLKEYLYNIDPDVEPLRSELQTGKFTILPAR------ 178
            ||::.:                               .|......|...||..|.....
Zfish  3621 HTSSTE-------------------------------SPTSTSSTSHTSTGSSTTSQTTAYSSTD 3654

  Fly   179 ----TSSGAAIALFTANRHSPLSVSHTTTLQGIVYQLDSALQDSETQRAGLVFIYDMSGSKYSNF 239
                ||:.:..:..|:..|: ::.||||...|   ...:...||.||.:|..   ..|||..::.
Zfish  3655 TTDYTSTDSQTSTPTSTSHT-ITSSHTTQSTG---PTSTETTDSSTQTSGST---QTSGSTQTSG 3712

  Fly   240 DYDLSQKILTLLKGGYPARLKKVLIVTAPLWFKAPFKILRLFVREKLRERVFTVSVPQLALHVPR 304
            ....|....|
Zfish  3713 STQTSGSTQT------------------------------------------------------- 3722

  Fly   305 KALPIHLGGTLEVDHATWLLSCRQ----SMTNREDELLANIVGVGGGSGSGSAAGSAAIVSTNGT 365
             :......|:.:...:|...|..|    :.|:...:...:|...|....|||...|.:..::..|
Zfish  3723 -SSSTQTSGSTQTSGSTQTSSSTQTSSSTQTSGSTQTSGSIQTSGSAQTSGSTQTSGSTQTSGST 3786

  Fly   366 ETEAA--TTAATIISAVHQLGDNNTTVVTVSNGVGPAGSASGGATTAASAATEPNENITINGLSP 428
            :|..:  |:.:|..|...|...::|...|......|:.::|....|..:.:|....:.:....|.
Zfish  3787 QTSGSTQTSGSTQTSGSTQTSVSSTATATTYTPPMPSSASSTATFTTHTPSTVSTTSASTTATST 3851

  Fly   429 SHRQAANNSSSSSSSAATV----ANP-----------------------------------LKLN 454
            :|.....:::|:|::|||.    .:|                                   .|||
Zfish  3852 THTPTTVSTTSASTTAATTDSNQTSPTTTPKPDLNWKFTVSDITTSSVNLTWQAIDKDTAYYKLN 3916

  Fly   455 -TSGSADNNSTITNA------TTAAG-------------------------------AAGAAAGT 481
             |.|....|.|.|.|      ..|||                               :...|:..
Zfish  3917 WTDGGTQRNGTNTTALFYWVTNLAAGVNYTFCITAVNQLSVESDPVCISSFTKPNVVSNLTASKV 3981

  Fly   482 TTNGGGEFWSENPP-----------------------------------------SSASSGFSDD 505
            ||:.....|  |.|                                         |:.:.|...:
Zfish  3982 TTSSVTLHW--NAPSGPIDYYLVEWSVQRSTDRRTNETFYVITDLMPATKYEIHVSAVTGGIKSE 4044

  Fly   506 --------DSLAG---------------------------------QEGDPKPIDQIVQMVKQR- 528
                    |..||                                 ::...:..|..|.|:::.
Zfish  4045 LVFLTVLTDVEAGPTSTNNTGMIVGIVLTLICLIAAIILFVFFYSRRQSKKQYPDIPVHMIRKNA 4109

  Fly   529 ----------------GRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLA 577
                            ...|..:||.::::...:.:...|....|..||||::||.||.|||.|:
Zfish  4110 LKVEDYEEYFKRNSADSNCGFAEEYEELKSVGTQQSKAAALAIENKAKNRYSNVLPYDASRVKLS 4174

  Fly   578 HEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKC 642
             ..|....||||||.|.||..:..:|:.|||||.|..:|||||||::...|||.|:..|.|||||
Zfish  4175 -MCGSPFDDYINANHVPGYNSRKEFIAAQGPLPVTLNEFWRMIWEKNVYTIVMLTKCNEMGRVKC 4238

  Fly   643 GQYWEPTEESSLEFGDYHVRTISVECN-----EDYMVASLELRNIKTDEIRNVSHWQFTSWPDYG 702
            .:|| |:..|       |...|||...     :|:.:....::|:||.|.|.|..:.||:|||:|
Zfish  4239 EKYW-PSATS-------HYNNISVTTTSEIELDDWTIRDFRIKNVKTAETRYVRQFHFTAWPDHG 4295

  Fly   703 VPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLED 767
            ||.:...:::|...|||...|           :.|..|.|||||||:|||||||.:|....::|.
Zfish  4296 VPETTEILIDFRHLVREHMDQ-----------YSRHSPTVVHCSAGVGRTGTFIAIDHLSFQIER 4349

  Fly   768 VGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSR 808
            ....||.|.|..:|..||..:|..||||:.|....:...||
Zfish  4350 DSMVDIYGIVHDMRMHRALMVQTEDQYVYLHQCAYDLIRSR 4390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	2/29 (7%)
		SEC14	170..314	CDD:469559	21/153 (14%)
		PTPc-N9	529..799	CDD:350391	109/274 (40%)
ptprjb.1	XP_073799246.1	None