Protein Alignment Ptpmeg2 and ptpn9a

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_005163030.1
• Gene: ptpn9a / 100526653
• ZFINID: ZDB-GENE-101027-1
• Length: 571
• Species: Danio rerio
• Alignment Length: 706
• Identity: 291/706 - (41%)
• Similarity: 373/706 - (52%)
• Gaps: 171/706 - (24%)

  Fly   110 GAAPVRRHISHTTAVKFLYARKFDIPRAVSLYEQHEQIRLKEYLYNIDPDVEPLRSELQTGKFTI 174
            |.:|    :|...|||||.|||||:.||:.|:..:.:.||:|.:..:.|..|||||||.:||||:
Zfish    29 GVSP----LSWDVAVKFLMARKFDVLRAIELFHSYRETRLREGIVKLQPHKEPLRSELLSGKFTV 89

  Fly   175 LPARTSSGAAIALFTANRHSPLSVSHTTTLQGIVYQLDSALQDSETQRAGLVFIYDMSGSKYSNF 239
            |..|..|||:|||:||..|.|....:...||.:.|.||.|::..||||.||||||||:||.|:||
Zfish    90 LGVRDPSGASIALYTAKLHHPSKTGNHVVLQALFYLLDRAVESFETQRNGLVFIYDMAGSNYTNF 154

  Fly   240 DYDLSQKILTLLKGGYPARLKKVLIVTAPLWFKAPFKILRLFVREKLRERVFTVSVPQLALHVPR 304
            :.|||:|||.||||.:||||||||||.||:||:.|:.:|.|.::|||||||..|.:..|..|:||
Zfish   155 ELDLSKKILNLLKGAFPARLKKVLIVGAPVWFRVPYNLLSLLLKEKLRERVQMVKMADLRQHLPR 219

  Fly   305 KALPIHLGGTLEVDHATW---LLSCRQSMTNREDELLANIVGVGGGSGSGSAAGSAAIVSTNGTE 366
            ..||.||||.|.:|...|   |||.:....:..|||    ||:
Zfish   220 DCLPEHLGGCLPLDVHNWNLQLLSEQNGRVDPVDEL----VGI---------------------- 258

  Fly   367 TEAATTAATIISAVHQLGDNNTTVVTVSNGVGPAGSASGGATTAASAATEPNENITINGLSPSHR 431
                                                              |.||.:|:
Zfish   259 --------------------------------------------------PLENTSIH------- 266

  Fly   432 QAANNSSSSSSSAATVANPLKLNTSGSADNNSTITNATTAAGAAGAAAGTTTNGGGEFWSENPPS 496
                                                                         .|.:
Zfish   267 -------------------------------------------------------------TPGA 270

  Fly   497 SASSGFSDDDSLAGQEGDPKPIDQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKN 561
            .|.|                 :.:::..:.:..|.|:..||.::|...|.|||..|....|..:|
Zfish   271 EAMS-----------------LAELMAHLNRAQRSGIYLEYEELRREQPPGTFTCALAAHNQERN 318

  Fly   562 RYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCL 626
            ||.||||.|.:||.|... .:|.||||||:|:||||||||||.|||||.||..|||||:|||:.|
Zfish   319 RYGDVLCLDQTRVRLKAR-RNERSDYINASFMDGYKQKNAYIGTQGPLEKTYGDFWRMVWEQNVL 382

  Fly   627 VIVMTTRVMERGRVKCGQYWEPTEESSLE-FGDYHVRTISVECNEDYMVASLELRNIKTDEIRNV 690
            |||||||..|.||.|||||| |.||...| :|...|....|:.:..|...:|||.|.:|.|.|.|
Zfish   383 VIVMTTRTDEGGRRKCGQYW-PQEEGGQEVYGYIAVVNHRVDNHAHYNQTTLELHNTETFEQRQV 446

  Fly   691 SHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTF 755
            :|:||.|||||||||||:::::||..|:.:|...||..|..|.|||.|||:||||||||||||||
Zfish   447 THFQFLSWPDYGVPSSAVSLIDFLGAVKHQQQWAVQAFGTQWRGHPLGPPMVVHCSAGIGRTGTF 511

  Fly   756 ITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGML 811
            ..||||:|:|:||||.:|..||.::|||||:|||.|:||.|||.|::|:|..:|:|
Zfish   512 CALDICLSQLQDVGTLNICQTVRRMRSQRAFSIQTPEQYYFCHAAILEHAQRQGLL 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	14/29 (48%)
		SEC14	170..314	CDD:469559	83/143 (58%)
		PTPc-N9	529..799	CDD:350391	156/270 (58%)
ptpn9a	XP_005163030.1	CRAL_TRIO_N	11..59	CDD:215024	16/33 (48%)
		SEC14	81..231	CDD:214706	86/149 (58%)
		PTPc-N9	286..554	CDD:350391	155/269 (58%)