Protein Alignment Ptpmeg2 and ptprt

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_004918595.1
• Gene: ptprt / 100496210
• XenbaseID: XB-GENE-5717729
• Length: 1486
• Species: Xenopus tropicalis
• Alignment Length: 915
• Identity: 235/915 - (25%)
• Similarity: 354/915 - (38%)
• Gaps: 221/915 - (24%)

  Fly    63 STSSSSASS------TQNLIAVVPPQLQQLQVQLPAPGGGGGAGAGGGGGGGGG---------AA 112
            :||.|.|.:      |..|..:.|....:::|.|..|        |.||.|..|         |.
 Frog   320 TTSGSWAETHVMDGPTYKLWHLDPDVEYEIRVLLTRP--------GEGGTGPPGPPLTTRTKCAD 376

  Fly   113 PVRRHISHTTAVKFLYARKFDI---PRAVSLYEQHEQIRLKEYLYNIDPD-VEPLRSELQTGKFT 173
            ||  |......:..:.||:..:   |...|:...|.......|.:.:..| ||.....|.:..:|
 Frog   377 PV--HGPQNVELVDIRARQLTLQWEPFGYSVTRCHSYNLTLHYSFQLGEDRVEAEELVLTSSHYT 439

  Fly   174 ILPARTSSGAAIALFTAN----RHSPLSVSHT----------TTLQGIVYQLDSALQ---DSETQ 221
            :...|..:...:.|...|    :.|...|.||          .::||..::....||   .:||.
 Frog   440 LRGLRPHTAVYLRLALCNPEGRKESGEIVVHTEEDVPGPIPLESIQGGPFEEKIYLQWKAPNETN 504

  Fly   222 RAGLVFIY--------------DMSGSK-----------------YSNFDYDLSQKILTLLKGGY 255
              |::.:|              |:|..|                 |....|..:.:..|....|.
 Frog   505 --GVISMYEVTYKAVGSLDPSADLSNQKGRIFKLRNETHHLFVGLYPGSTYSFTIRASTSKGFGP 567

  Fly   256 PARLKKVLIVTAP-------------------LWFK------APFKILRLFVREKLRERVFTVSV 295
            |...:....:.||                   :|.|      ||....:|.|:|:..:|....:.
 Frog   568 PVTARIATKIAAPSLTDSEAEAPLNETESTITVWLKPAQSRGAPVSAYQLVVKEERAQRSGRAAD 632

  Fly   296 PQLALHVP---RKALPIHLGGTLEVDH--ATWL----LSCRQSMT---NREDELLANIVGVGGGS 348
            ......||   |.|      .:||..|  |..|    |:..|..|   ||...        |..:
 Frog   633 GSGCFPVPVGYRNA------SSLESSHYFAAELKPSQLAVTQPFTVGDNRTYN--------GYWN 683

  Fly   349 GSGSAAGSAAI----VSTNGTETE--------AATTAATIISAVHQLGDNNTTVVTV-SNGVGPA 400
            ...|...|.:|    :||...||:        .|.||..:....|......|...|: ||.|.|.
 Frog   684 PPLSPVKSYSIYFQALSTANGETKIGCVRLASKAATAGLLPITRHPPSQPVTGASTLNSNTVEPE 748

  Fly   401 GSASGGATTAASAATEPNENITINGLSPSHRQAAN----------------NSSSSSSSAATVAN 449
            ..|.....||...|......|.:.|...:.::..|                ..|.|......||:
 Frog   749 KPADSTVQTAGVIAGMLMFIIILLGAMMTIKRRRNVYSYSYYLKLAKKQKETQSGSQREMGLVAS 813

  Fly   450 PLKLNTSGSADNNSTITNATTAAGAAGAAAGTTTNGGGEFWSENPPSSASSGFSD--------DD 506
            ....:...|..|..|.::.....|.:.::..:.:........::..||..|..||        |:
 Frog   814 DKSSSKLSSTRNEDTFSSCQDVNGFSSSSPCSFSVQSKNIQGKSLLSSCYSVSSDTVPSLALLDN 878

  Fly   507 S-----------------------LAGQEGDPKP-------IDQIVQMVKQRGRHGLIKEYADIR 541
            |                       :|...|..:|       :..|.||.:.:| :|..:||..:
 Frog   879 SHVDMNQPTLTIQTHPYRTCEPLEMAYPRGQLQPAIRVADLLQHITQMKRGQG-YGFKEEYEAL- 941

  Fly   542 NRAPEG---TFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYI 603
               |||   ::..|:...|..||||.:::.||||||.|...:||..|||||||:||||.:...||
 Frog   942 ---PEGQTASWDTAKEDENRNKNRYGNIISYDHSRVRLQQIEGDPHSDYINANYVDGYHRPRYYI 1003

  Fly   604 STQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVEC 668
            :||||:.:|.:|||||||:::.:.:||.|.::|.|||||.:||....|   .:||..|..|..|.
 Frog  1004 ATQGPMQETVKDFWRMIWQENSVSVVMVTNLVEVGRVKCVRYWPDETE---VYGDIKVSLIETEP 1065

  Fly   669 NEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWA 733
            ..:|::.:..::...:.:||.:..:.||||||:|||..|..:|.|:::|:             :.
 Frog  1066 LAEYVIRTFTVQKKGSHDIREIRQFHFTSWPDHGVPCYATGLLGFIRQVK-------------FL 1117

  Fly   734 GHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCH 798
            ..|...||.||||||.||||..|.:||.:...|:.|..||...|.::|:||...:|..:||||.|
 Frog  1118 NPPDAGPITVHCSAGAGRTGCLIAIDIMLDMAENEGVVDIFNCVRELRAQRVNMVQTEEQYVFVH 1182

  Fly   799 LALIE 803
            .|::|
 Frog  1183 DAILE 1187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	6/32 (19%)
		SEC14	170..314	CDD:469559	38/219 (17%)
		PTPc-N9	529..799	CDD:350391	109/272 (40%)
ptprt	XP_004918595.1	MAM	21..180	CDD:214533
		Ig	187..272	CDD:472250
		FN3	280..351	CDD:214495	7/30 (23%)
		FN3	381..471	CDD:238020	16/89 (18%)
		fn3	493..568	CDD:394996	13/76 (17%)
		R-PTPc-T-1	955..1191	CDD:350478	104/249 (42%)
		R-PTPc-T-2	1276..1481	CDD:350482