Protein Alignment Ptpmeg2 and ptpn9

DIOPT Version :10

• Sequence 1: NP_572576.1
• Gene: Ptpmeg2 / 31907
• FlyBaseID: FBgn0028341
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_012821586.2
• Gene: ptpn9 / 100158581
• XenbaseID: XB-GENE-967840
• Length: 569
• Species: Xenopus tropicalis
• Alignment Length: 698
• Identity: 276/698 - (39%)
• Similarity: 364/698 - (52%)
• Gaps: 168/698 - (24%)

  Fly   118 ISHTTAVKFLYARKFDIPRAVSLYEQHEQIRLKEYLYNIDPDVEPLRSELQTGKFTILPARTSSG 182
            :|...|||||.|||||:.|||.|:..:.:.|.:|.:..::|..|||.|||.:||||:|..|..:|
 Frog    32 LSWDIAVKFLMARKFDVVRAVELFHSYRETRHREGIVRLNPLQEPLLSELLSGKFTVLSVRAPTG 96

  Fly   183 AAIALFTANRHSPL-----SVSHTTTLQGIVYQLDSALQDSETQRAGLVFIYDMSGSKYSNFDYD 242
            |:||:|||..|.|.     ...| |.||.:.|.||.|::..:|||.||.|||||.||:|:||:.:
 Frog    97 ASIAIFTAKLHHPARRNSRQAQH-TVLQALFYLLDRAVESVDTQRNGLFFIYDMGGSQYNNFELE 160

  Fly   243 LSQKILTLLKGGYPARLKKVLIVTAPLWFKAPFKILRLFVREKLRERVFTVSVPQLALHVPRKAL 307
            ||:|||:||:|.:||||||||||:.|:||:.|:.::.|.::|||||||..|:..:|..|:|.:.|
 Frog   161 LSKKILSLLRGAFPARLKKVLIVSPPVWFRVPYSVISLLLKEKLRERVHMVNASELLEHLPPQCL 225

  Fly   308 PIHLGGTLEVDHATW---LLSCRQSMTNREDELLANIVGVGGGSGSGSAAGSAAIVSTNGTETEA 369
            |..|||.|..|..:|   ||..|....:..|||   ::.:||
 Frog   226 PESLGGLLPWDPGSWNCLLLPGRAGKPDPLDEL---VMVLGG----------------------- 264

  Fly   370 ATTAATIISAVHQLGDNNTTVVTVSNGVGPAGSASGGATTAASAATEPNENITINGLSPSHRQAA 434
                                        ||:||.                          ||..|
 Frog   265 ----------------------------GPSGSV--------------------------HRPGA 275

  Fly   435 NNSSSSSSSAATVANPLKLNTSGSADNNSTITNATTAAGAAGAAAGTTTNGGGEFWSENPPSSAS 499
            .                                            |.|
 Frog   276 R--------------------------------------------GMT----------------- 279

  Fly   500 SGFSDDDSLAGQEGDPKPIDQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYT 564
                              :.|:.:.|.:.||.|..:||.::|.:.|||||..:....|..:|||.
 Frog   280 ------------------LAQLKEYVGRVGRRGTYEEYEEMRKKQPEGTFTVSLAPVNRDRNRYG 326

  Fly   565 DVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIV 629
            ||||.|.:||.|...:..|.||||||:|:|||.|||.||.|||||.||..|||:|||||:.||||
 Frog   327 DVLCLDQTRVKLKRLNWHERSDYINASFMDGYLQKNMYIGTQGPLEKTFSDFWQMIWEQNVLVIV 391

  Fly   630 MTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQ 694
            |||||.|.|..||||||..:..|...:|...|...:.|..:.|...:|||...:..:.|.:||.|
 Frog   392 MTTRVEEGGHRKCGQYWPLSTGSLSTYGAVTVTNKATENYQHYRKTTLELSTRQGKDKRLISHLQ 456

  Fly   695 FTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLD 759
            |.||||:||||||.|::||...|:::|.:||:.||..|.|.|.|||.||||||||||||||.|||
 Frog   457 FLSWPDFGVPSSASALINFRGAVKKEQRRLVEELGTQWRGPPGGPPFVVHCSAGIGRTGTFCTLD 521

  Fly   760 ICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYS 807
            ||:|:|:||||..|:.||:|:|.|||:|||.|:||.||:.:::||..|
 Frog   522 ICLSQLDDVGTVSIQETVQKMRQQRAFSIQTPEQYYFCYTSILEYTTS 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024	15/25 (60%)
		SEC14	170..314	CDD:469559	76/148 (51%)
		PTPc-N9	529..799	CDD:350391	150/269 (56%)
ptpn9	XP_012821586.2	CRAL_TRIO_N	10..58	CDD:215024	15/25 (60%)
		SEC14	80..234	CDD:214706	79/154 (51%)
		PTPc-N9	291..561	CDD:350391	150/269 (56%)