Protein Alignment CG42797 and UBE3B

DIOPT Version :9

• Sequence 1: NP_572574.2
• Gene: CG42797 / 31905
• FlyBaseID: FBgn0261931
• Length: 1426
• Species: Drosophila melanogaster
• Sequence 2: NP_569733.2
• Gene: UBE3B / 89910
• HGNCID: 13478
• Length: 1068
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 126/393 - (32%)
• Similarity: 196/393 - (49%)
• Gaps: 39/393 - (9%)

  Fly  1065 PHKLKLHIRRSHLLEDAFRRIMSANKKDLQRGRLAV-----LWDTEEGLDYGGPSREFFFLLSRE 1124
            ||...:.||||.:|||.:.::...::..: :|.:.|     |...|.|:|..|..:||...:.:.
Human   678 PHVTHITIRRSRMLEDGYEQLRQLSQHAM-KGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKR 741

  Fly  1125 LFNPYYGLFEYSANDTYTVQVSPLSAFVDNCHDWFRFSGRVLGLALVHQYLLDAFFTRPFYKALL 1189
            :|:|...||:.::.|. .:..||.|...:|....|.|.|::||.|:....::|..|...|...||
Human   742 VFDPALNLFKTTSGDE-RLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQLL 805

  Fly  1190 R-----LPVALSDLESLDNEFHQSLQWIR--DNDIGTGVDLGLTFCVTEELLGSVVDRELKPGGK 1247
            .     ...::.:|.|||:||:::|..|:  |.||   .|||||....|:::|.:|..||.||||
Human   806 GHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDI---TDLGLTLSYDEDVMGQLVCHELIPGGK 867

  Fly  1248 NIIINEKNKKEYLERMIKWRLERGVQEQTESLVRGFYEVIDSRLVSVFDARELELVIAG-TAEID 1311
            .|.:..:||..|:..|..:|:...::.||.:|:.||..:|....:.:|...||:.:|:| .||||
Human   868 TIPVTNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDNAEID 932

  Fly  1312 TNDWRLNTEYRSGYHDNHQVIVWFWQVI-ERFSNEQRLRLLQFVTGTSSIPYEGFSALR------ 1369
            ..|.:.:|.|..|:|.:|:||:|.|.:: ..|:.::|...|:|||..|..|..||:.|:
Human   933 LEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPDERAMFLKFVTSCSRPPLLGFAYLKPPFSIR 997

  Fly  1370 --------------GSTGPRRFCIEKWGKPNALPRAHTCFNRLDLPPYPTPELLYEKLLLAVEET 1420
                          ||.....|.|.|......||.:.||||.|.||.|....:|.|||..|:...
Human   998 CVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMN 1062

  Fly  1421 NTF 1423
            ..|
Human  1063 TGF 1065

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42797	NP_572574.2	WW	638..667	CDD:278809
		HECTc	1068..1424	CDD:238033	124/390 (32%)
		HECTc	1092..1423	CDD:214523	116/364 (32%)
UBE3B	NP_569733.2	HECTc	682..1066	CDD:238033	124/389 (32%)
		HECTc	707..1065	CDD:214523	116/361 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810