Protein Alignment Hecw and UPL7

DIOPT Version :10

• Sequence 1: NP_572574.2
• Gene: Hecw / 31905
• FlyBaseID: FBgn0261931
• Length: 1426
• Species: Drosophila melanogaster
• Sequence 2: NP_190877.1
• Gene: UPL7 / 824475
• AraportID: AT3G53090
• Length: 1142
• Species: Arabidopsis thaliana
• Alignment Length: 964
• Identity: 227/964 - (23%)
• Similarity: 365/964 - (37%)
• Gaps: 277/964 - (28%)

  Fly   690 YQSIRRTI-TNESRAAQLYNLPTSANSNANSTAPAAPPPATAIHPAILMLCRPD-------FYSL 746
            |.::||.| |......:...:.|||       ...|..|.....||.:...:||       :.||
plant   227 YSAVRRYIKTLTKHTDERLVITTSA-------VTLALRPFHVKQPAFVDDNQPDTNLAVEEYVSL 284

  Fly   747 LHTNEAALAIYNRNA---ALKHMVMRIRRDPPCFQRYQYNKDLVALVNTFAQM--------SREL 800
            :.| ...|..|..:|   ||||..:.:    |.|......||  .::|..::|        :.|:
plant   285 ILT-IPRLVCYLPSALIRALKHKSILM----PSFHTILLLKD--KILNIISEMENSEKQSCTMEI 342

  Fly   801 PSC-W--------ETKLDQSGKQFFIDHQHRRTSFMDPR---------LPVECPRVVRHRQQHSQ 847
            ||. |        .|..:              |.||||:         |.|..  :|...:....
plant   343 PSVGWVIGNIISLATVSE--------------TDFMDPQESNPEMFYVLYVHV--IVTLAENLLS 391

  Fly   848 QQSSVGYYYPDL-VDGNCLSATSGHINASPASSVSGVPPLPP---------------------PR 890
            |..|||  ..|: :|   :.|||.......:..:|.|..|.|                     ..
plant   392 QVESVG--IQDIHLD---IEATSNETEKGNSVKISFVEMLRPVCQQWHLAKLLAASGKEIRVIAD 451

  Fly   891 PSSSSSSSRSSHGHG-------HNCNTTSAISCALNADRSAYGAAGMAS---------------- 932
            ..:|:||.:.|...|       ::|  ...|.|.:|..........|.|
plant   452 KDASTSSKKGSETLGLLDIARLYSC--MLRIFCVMNPVLGPLPVLNMLSFCPGYIVSLWNSLESV 514

  Fly   933 ----AGATA--AGYEDVPIAYN-----EKVIAFLRQPNI---LEILRERQG------QHTM---- 973
                .|.||  |.:.....::|     ||.:..|:..::   :.:|.:..|      :|..
plant   515 LLPENGCTADDASHGSAKTSWNTRSPSEKKLKHLKNDSVNKWVNVLNKFSGKSPGPREHVECTSD 579

  Fly   974 ---SRQLREKIN----ILRVEGVPALERLGHDLQLTILLSLF-----------------EQEIMG 1014
               |.|:.|..|    :..:.|.|    :|...:::.||.||                 |:::..
plant   580 QPGSGQVNESTNDVWDVETLRGGP----VGISKEVSCLLHLFCATYAHLLVVLDDIQFYEKQVPF 640

  Fly  1015 FVPIEER-----------------SPQGSPVLNSRM-----------------------PQRA-- 1037
            .:..::|                 .|:...:::|.:                       |.|.
plant   641 MLEKQQRIASMLNTLVYYGLLRGTGPESRQLMDSAIRCLHLLYERDCRHPFCASALWLSPGRTSR 705

  Fly  1038 PP---------------------------------PFR------RDFEAKLRSFYRKLESKGYGQ 1063
            ||                                 ||.      |:|.:|.:: .||:..:....
plant   706 PPIAFAARTHEVLPTSDVLTTPSMGSVITITPHVFPFEERVHVFREFISKDKA-SRKMAGEVDAP 769

  Fly  1064 GPHKLKLHIRRSHLLEDAFRRIMSANKKDLQRGRLAVLWDT---EEGLDYGGPSREFFFLLSREL 1125
            |...:::.:||.|::||.|:::.|...:......::.:.::   |.||||||.|:||...:::..
plant   770 GARSIEIVVRRGHVVEDGFQQLNSIGSRLKSSIHVSFVNESGLPEAGLDYGGLSKEFLTDITKAA 834

  Fly  1126 FNPYYGLFEYSANDTYTVQVSPLSAFVDNCHDWFRFSGRVLGLALVHQYLLDAFFTRPFYKALLR 1190
            |...||||..:......:..||.:..::|......|.||::|.||....|||..|:..|.:.||.
plant   835 FATEYGLFSQTPTSDRLLVPSPSARHLENGIQMIEFLGRIVGKALYEGILLDYSFSHVFIQKLLG 899

  Fly  1191 LPVALSDLESLDNEFHQSLQWIRDNDIGTGVDLGLTFCVTEELLGSVVDRELKPGGKNIIINEKN 1255
            ....:.:|..||.|.:::|.:::..| |...:|.|.|.||||..|.:...|||||||:..:..:|
plant   900 RYSFIDELSGLDPELYRNLMYVKHYD-GDLKELCLDFTVTEEFCGKMSIIELKPGGKDTSVTNEN 963

  Fly  1256 KKEYLERMIKWRLERGVQEQTESLVRGFYEVIDSRLVSVFDAREL-ELVIAGTAEIDTNDWRLNT 1319
            |.:|:..|..::|.|.:...:.:..||..::|....:.:|:|.|. :|:..|..:||.:|.|.||
plant   964 KMQYIHAMADYKLNRQIVPFSNAFYRGLTDLISPAWLKLFNAHEFNQLLSGGNHDIDVDDLRRNT 1028

  Fly  1320 EYRSGYHDNHQVIVWFWQVIERFSNEQRLRLLQFVTGTSSIPYEGFSALRGSTGPRRFCIEK--- 1381
            :|..||.|:.:.|..||:|::.|...:|..||:|||..|..|..||..|:.:     |.|.|
plant  1029 KYTGGYSDSSRTIKIFWEVMKGFEPSERCLLLKFVTSCSRAPLLGFKYLQPT-----FIIHKVSC 1088

  Fly  1382 ----WG-----KPNALPRAHTCFNRLDLPPYPTPELLYEKLLLAVEETNTFGIE 1426
                |.     ....||.|.||:|.|.||.|.....:.||||.|:  |:..|.|
plant  1089 DTSLWAAIGGQDVERLPSASTCYNTLKLPTYKRASTMREKLLYAI--TSNAGFE 1140

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hecw	NP_572574.2	PHA03247	<411..562	CDD:223021
		WW	638..667	CDD:459800
		HECW1_helix	738..794	CDD:465766	17/65 (26%)
		HECTc	1068..1424	CDD:238033	120/371 (32%)
UPL7	NP_190877.1	IQCD	33..>62	CDD:467745
		HECTc	774..1140	CDD:238033	121/373 (32%)