Protein Alignment CG42797 and hace1

DIOPT Version :9

• Sequence 1: NP_572574.2
• Gene: CG42797 / 31905
• FlyBaseID: FBgn0261931
• Length: 1426
• Species: Drosophila melanogaster
• Sequence 2: XP_012818577.2
• Gene: hace1 / 734146
• XenbaseID: XB-GENE-5757512
• Length: 1012
• Species: Xenopus tropicalis
• Alignment Length: 1006
• Identity: 256/1006 - (25%)
• Similarity: 413/1006 - (41%)
• Gaps: 315/1006 - (31%)

  Fly   671 PSGGPAGREQH-HRQQLDRRYQSIRRTITNESRAAQLYNLPTSANSNANSTAPAAPPPATAIHPA 734
            |..||.|..|: ...:::|..:.:.| :|...|.|:...||   ..|..:.....|......|.:
 Frog    53 PRPGPGGLSQYPGLPRMERAMEQLNR-LTRSLRRARTVELP---EDNETAVYTLMPMVMADQHRS 113

  Fly   735 IL-MLCRPDF---YSLLHTNEAALAIYNRNAALKHMVMRIRR--DP------------------- 774
            :| :|....|   |:......:.|.|.....:::.:|:.::|  ||
 Frog   114 VLELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKRGADPNYQDISGCTPLHLAARNGQ 178

  Fly   775 -PCFQR-YQYNKD--------LVAL----VNTFAQMSREL----------PSCWETKLD---QSG 812
             .|..: .:||.|        |.|:    ||...::..:|          .:..:|.|.   |:|
 Frog   179 KKCMSKLLEYNADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTNVDVEDAMGQTALHVACQNG 243

  Fly   813 KQ-------------------------FFIDHQHRRTS---------FMDPR---LPVE------ 834
            .:                         |...|..|.|:         ::..:   .|::
 Frog   244 HKTTVLCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGG 308

  Fly   835 ----CPRVVRH----------------------RQ--QHSQQQSSVGYYYPDLVDGNC-LSATSG 870
                |..:::|                      ||  :|..|||.|.|.  .::.|.. ::.|:|
 Frog   309 YGETCDILIQHHPRLFQTLIQMTQNEDLRENTLRQVLEHLSQQSEVQYL--KILTGLAEVATTNG 371

  Fly   871 HINASPASS-----------------VSGVPPLPPPRPSSSSSSSRSSHGHGHNCNTT------- 911
            |...|.:||                 |..:.|          ||..:.:..|:|.|.|
 Frog   372 HKLLSISSSYEAQMKSLLRIVRIFCHVFRIGP----------SSPNNGNDMGYNGNKTPRNQVFK 426

  Fly   912 -----------------------------------------------------------SAISCA 917
                                                                       |.|:|.
 Frog   427 VRNVYDVFRKINIKEMNLPNHTLIYQATSEQDPLELLWHSLDEWLVLIATELTKNKRDSSNIACI 491

  Fly   918 L------------NADRSAYGAAG----MASA-------GATAAGYEDVPIAYNEKVIAFL--RQ 957
            |            .|.:||.|.:|    ::|:       ..:|||.:: |:|..:.||:..  |.
 Frog   492 LLKQNQLDQQDISLAHQSAIGESGSYDHLSSSTRAEDFESCSAAGKQE-PVADGQDVISMTANRL 555

  Fly   958 PNILEILRERQGQHTMSRQLREKINILR-VEGVPALERLGHDLQLTILLSLFEQEIMGFVPIEER 1021
            ..:::..     ....|.|:.:.:...| :|.|     ..||..|...::              |
 Frog   556 SAVIQAF-----YMCCSCQMPQGMTSPRFIEFV-----CKHDDVLKCFVT--------------R 596

  Fly  1022 SPQ----------GSPVLNSRMPQ--RAPPPFRRDFEAKLRSFYRKLESKGYGQGPHKLKLH--- 1071
            :|:          ..|.|.||...  :|.|     |:.:...||..|.:   || |....:|
 Frog   597 NPKIIFDHFHFLLECPELMSRFMHIIKAQP-----FKERCEWFYEHLLA---GQ-PDSDMVHRPV 652

  Fly  1072 -------IRRSHLLEDAFRRIMSANKKDLQRGRLAVLWDTEEGLDYGGPSREFFFLLSRELFNPY 1129
                   :.|..:...:...:..:|.:.|::| :||.:..|||:.. |..||:|.:||.|:.||.
 Frog   653 NENDILLVHRDSIFRSSCEVVFKSNCEKLKQG-IAVRFHGEEGMGQ-GVVREWFDILSSEIINPD 715

  Fly  1130 YGLFEYSANDTYTVQVSPLSAFVDNCHDWFRFSGRVLGLALVHQYLLDAFFTRPFYKALLRLPVA 1194
            |.||..||:.| |.|.:..|:...:..::|||:|.:|||||.|:.|::.:|||.|||.:|.:||.
 Frog   716 YALFTQSADGT-TFQPNSNSSVNPDHLNYFRFAGEILGLALYHRQLVNIYFTRSFYKHILGIPVN 779

  Fly  1195 LSDLESLDNEFHQSLQWIRDNDIGTGVDLG--LTFCVTEELLGSVVDRELKPGGKNIIINEKNKK 1257
            ..|:.|:|.|:.::||||.||||.   |||  |||.|..::.|::.:..|||||.:|::.::||.
 Frog   780 YQDVASIDPEYAKNLQWILDNDIS---DLGLELTFSVETDVFGAMEEVPLKPGGASILVTQENKA 841

  Fly  1258 EYLERMIKWRLERGVQEQTESLVRGFYEVIDSRLVSVFDARELELVIAGTAEIDTNDWRLNTEYR 1322
            ||::.:.:.|:.|.:|.|....::||:..|...|:.:||..||||:::|..|||.|||..||||.
 Frog   842 EYVQLVTELRMTRAIQPQINGFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWMKNTEYT 906

  Fly  1323 SGYHDNHQVIVWFWQVIERFSNEQRLRLLQFVTGTSSIPYEGFSALRGSTGPRRFCIEKWG-KPN 1386
            |||..:.|||.|||:|::..:.|:|:.|||||||:|.:|:.||:.:.|.:|.:.|.|.... .||
 Frog   907 SGYERDDQVIQWFWEVVQELTQEERVLLLQFVTGSSRVPHGGFAYIMGGSGLQNFTIAAVAYTPN 971

  Fly  1387 ALPRAHTCFNRLDLPPYPTPELLYEKLLLAV 1417
            .||.:.||.|.|.||.||:.|:|.::||:|:
 Frog   972 LLPTSSTCINMLKLPEYPSKEILKDRLLVAL 1002

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42797	NP_572574.2	WW	638..667	CDD:278809
		HECTc	1068..1424	CDD:238033	147/363 (40%)
		HECTc	1092..1423	CDD:214523	144/329 (44%)
hace1	XP_012818577.2	PLN03192	<19..289	CDD:215625	42/239 (18%)
		ANK repeat	134..163	CDD:293786	6/28 (21%)
		ANKYR	<160..288	CDD:223738	17/127 (13%)
		ANK repeat	165..196	CDD:293786	4/30 (13%)
		ANK repeat	198..229	CDD:293786	5/30 (17%)
		ANK repeat	231..262	CDD:293786	4/30 (13%)
		ANK repeat	264..289	CDD:293786	4/24 (17%)
		HECTc	657..1006	CDD:238033	146/352 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000080
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910