DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42797 and wwtr1

DIOPT Version :9

Sequence 1:	NP_572574.2	Gene:	CG42797 / 31905	FlyBaseID:	FBgn0261931	Length:	1426	Species:	Drosophila melanogaster
Sequence 2:	NP_001032785.1	Gene:	wwtr1 / 568008	ZFINID:	ZDB-GENE-051101-1	Length:	391	Species:	Danio rerio

Alignment Length:	408	Identity:	87/408 - (21%)
Similarity:	140/408 - (34%)	Gaps:	115/408 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   519 TGSPLVCPPTPTHHARRHARLQAVTANSSLASGGAIPSDPPAVSSQLDYIYLQ--DGGQEQGQEQ 581
            :|:||  .|.|.|.. .|......|...:|.:....|......:..:...:.|  |.|....|..
Zfish     2 SGNPL--QPIPGHQV-IHVAKDLDTDLEALFNSVMNPKPSSWRNKDMPQSFFQEPDSGSHSRQSS 63

  Fly   582 SDEVVHISSTRLPSIPERSAAAAAAAAAAAAGAALMEPGTGTVSGSS-----------GAGAAGE 635
            :|     |.:..|.:..||.::.|:....|          |:|||.|           ....|.|
Zfish    64 AD-----SGSLPPRVHFRSRSSPASLQLPA----------GSVSGPSPGRLHSHTRHQSCDVAEE 113

  Fly   636 PPLPPAWEARMDSHGRIFYIDHTTRTTSWQRPGAAPSGGPAGREQHHRQQLDRRYQSIRRTITNE 700
            .||||.||.....:|:.::::|..:.|:|..|                          |:::|
Zfish   114 LPLPPGWEMAFTPNGQKYFLNHIEKITTWHDP--------------------------RKSMT-- 150

  Fly   701 SRAAQLYNLPTSANSNANSTAPAAPPPATAIHPAILMLCRPDFYSLLHTNEAALAIYNRNAALKH 765
            ...|||     |.::..::||        :|....:.|.:|:.            :.|:.|   |
Zfish   151 PSVAQL-----SLHNQVSNTA--------SIQQRSMALSQPNL------------VLNQQA---H 187

  Fly   766 MVMRIRRDPPCFQRYQYNKDLVALVNTFAQMSRELPSCWETKLDQSGKQFFIDHQHRRTSFMDPR 830
            ...:        |..|..:..|. |....|..::..|  :..::.|.:|    ||.:...   .|
Zfish   188 QQQQ--------QHLQQQQQQVP-VQVPVQAPQQQSS--QPMMNLSAQQ----HQQKMRL---QR 234

  Fly   831 LPVECPRVVRHRQQHSQQQSSVGYYYPDLVDGNCLSATSGHINASPASSVSGVP-----PLPPPR 890
            :.:|..|:.| ||:...:|.......|  :|.:.|...:..| .|||.|...:|     |.....
Zfish   235 IQMERERIQR-RQEELMRQEVALRQLP--MDSDNLPPVAPAI-GSPAMSAGNMPNNSADPFLNSG 295

  Fly   891 PSSSSSSSRSSHGHGHNC 908
            |..|...|..| |.|..|
Zfish   296 PYHSREQSTDS-GLGLGC 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42797	NP_572574.2	WW	638..667	CDD:278809	9/28 (32%)
		HECTc	1068..1424	CDD:238033
		HECTc	1092..1423	CDD:214523
wwtr1	NP_001032785.1	WW	115..146	CDD:197736	11/56 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810