DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42797 and herc5.1

DIOPT Version :9

Sequence 1:	NP_572574.2	Gene:	CG42797 / 31905	FlyBaseID:	FBgn0261931	Length:	1426	Species:	Drosophila melanogaster
Sequence 2:	XP_017211386.1	Gene:	herc5.1 / 559981	ZFINID:	ZDB-GENE-090311-56	Length:	884	Species:	Danio rerio

Alignment Length:	389	Identity:	107/389 - (27%)
Similarity:	174/389 - (44%)	Gaps:	38/389 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly  1044 DFEAKLRSFYRKLESKGYGQGPHKLKLHIRRSHLLEDAFRRIMSANKKDLQRGRLAVLWDTEEGL 1108
            :.|||. |:.|....||      :.:|.:||:.||||....:....::.|:...|::|:......
Zfish   522 NLEAKC-SYMRNRVWKG------RFELTVRRTALLEDCLCLLNPGTQQHLRDKWLSILFTENVSK 579

  Fly  1109 DYGGPSREFFFLLSRELFNPYYGLFEYSANDTYTVQVSPLSAFVDNCHDWFRFSGRVLGLALVHQ 1173
            ......|:||..:.:||.:|...||.|  ||..|:...|....|:. ..:|.| |.:.|||..:.
Zfish   580 RTDVHKRDFFLNVFKELCDPASQLFMY--NDNETMIWFPAKLTVEK-KKYFLF-GILCGLAFNNS 640

  Fly  1174 YLLDAFFTRPFYKALLRLPVALSDLESLDNEFHQSLQWIRD--NDIGTGVDLGLTFCVTEELLGS 1236
            .:::..|....:|.||.:..:|.|....:....:|||:|.:  ||:.....|.||      ::.|
Zfish   641 SVVNLPFPLALFKKLLNIKPSLEDFIEFNPVHGRSLQYILEYSNDVLEESSLPLT------IIWS 699

  Fly  1237 VVDRELKPGGKNIIINEKNKKEYLERMIKWRLERGVQEQTESLVRGFYEVIDSRLVSVFDARELE 1301
            ..:.:|.|......|...|:.::::..:.....:.|:|..|...|||:...:.|||.:|:..||.
Zfish   700 GSELDLDPAEPEQHITTSNRTKFVDEYVDHIFNQSVKEAFEEFRRGFFRGCEKRLVEMFEPEELR 764

  Fly  1302 LVIAGTAEIDTNDWRLNTEYRSGYHDNHQVIVWFWQVIERFSNEQRLRLLQFVTGTSSIPYEGFS 1366
            .|:.|..|.|.|..:.||.|...::.:|.||:.||:|.:..:..::...|.|:||...:|..|.|
Zfish   765 GVLVGNEEYDWNILKQNTTYEGVFNADHPVIISFWEVFDDLTPNEKKSFLLFLTGFERVPILGMS 829

  Fly  1367 A-------LRGSTGPRRFCIEKWGKPNALPRAHTCFNRLDLPPYPTPELLYEKLLLAVEETNTF 1423
            |       |..||            .:.||...||.:.|.||.|...|.|..|::.|:.....|
Zfish   830 AVKMRVTHLANST------------EDHLPETLTCHSLLQLPKYEKRETLRAKVIEAISHKRGF 881

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42797	NP_572574.2	WW	638..667	CDD:278809
		HECTc	1068..1424	CDD:238033	100/365 (27%)
		HECTc	1092..1423	CDD:214523	92/339 (27%)
herc5.1	XP_017211386.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810