DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42797 and Magix

DIOPT Version :9

Sequence 1:	NP_572574.2	Gene:	CG42797 / 31905	FlyBaseID:	FBgn0261931	Length:	1426	Species:	Drosophila melanogaster
Sequence 2:	NP_061302.2	Gene:	Magix / 54634	MGIID:	1859644	Length:	324	Species:	Mus musculus

Alignment Length:	315	Identity:	70/315 - (22%)
Similarity:	103/315 - (32%)	Gaps:	104/315 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   474 RGRGVGGALQDAVPPGTPTFHGQRPQQRLLKR-----VGGGAGAGAT-----GGATGSPLVCPPT 528
            ||...||.||.:..|        |.:| ||:|     :...|.|..|     .|||
Mouse    12 RGGRRGGGLQGSRSP--------RARQ-LLERLDARPLAARAAADLTALVRKAGAT--------- 58

  Fly   529 PTHHARRHARLQAVTANSSLASGGAIPSDPPAVSSQLDYIYLQDGGQEQGQEQSDEVVHISSTRL 593
                    .||:.....|.|.|     :|.....|:|.:..|.   :.:.|.|..|.:...:..|
Mouse    59 --------LRLRHTEGVSGLDS-----ADIEVTDSRLPHATLV---KHRPQHQRSETLGTWTEPL 107

  Fly   594 P----------SIPERSAAAAAAAAAAAAGAALMEPGTGTVSGSSGAGAAGEPPLP--------P 640
            |          .:|:.:...:.......||..|      |:||  |...:|:.||.        |
Mouse   108 PVTQNKASYALKVPQATGRFSVELTRGPAGFGL------TLSG--GRNVSGDAPLTVHGLLKDGP 164

  Fly   641 AWE-ARMDSHGRIFYID--HTTRTTSWQRPGAAPSGGP-----AGREQH-----------HRQQL 686
            |.. .|:.:...:.||:  .|...|..|......:|||     ..|.|.           || :.
Mouse   165 AQRCGRLQAGDLVLYINGQSTQGLTHAQVVERIRTGGPHLCLVLQRPQDMDGSRIKEVGGHR-KT 228

  Fly   687 DRRYQSIRRTITNESRAAQLYNLPTSANSNANSTAPAAPPPATAI--------HP 733
            ||........:.:.|..:.:::.|.:      .|:|...|.|.||        ||
Mouse   229 DRSLDPRGSRVESRSTISPVHHRPKT------RTSPRPSPEAVAIGHVVRAVEHP 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42797	NP_572574.2	WW	638..667	CDD:278809	9/39 (23%)
		HECTc	1068..1424	CDD:238033
		HECTc	1092..1423	CDD:214523
Magix	NP_061302.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26		6/13 (46%)
		PDZ	126..211	CDD:214570	21/92 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	216..263		8/53 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900