DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42797 and Herc3

DIOPT Version :9

Sequence 1:NP_572574.2 Gene:CG42797 / 31905 FlyBaseID:FBgn0261931 Length:1426 Species:Drosophila melanogaster
Sequence 2:NP_001102101.1 Gene:Herc3 / 362377 RGDID:1307803 Length:1050 Species:Rattus norvegicus


Alignment Length:520 Identity:143/520 - (27%)
Similarity:237/520 - (45%) Gaps:86/520 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   943 VPIAYNEKVIAFLRQPNILEILRERQGQHTMSRQLREKINILRVEGVPALERLGHDL----QLTI 1003
            :|:.:|..:.|.|:   :||.|              .|:| |:|:.|.      :|.    :::.
  Rat   579 IPVLFNNYMTATLK---LLEKL--------------YKVN-LKVKHVE------YDKFYIPEISS 619

  Fly  1004 LLSLFEQEIMGFVPIEERSPQGSPVLNSRMPQRAPPPFRRDFEAKLRSFYRKLESKG-------- 1060
            |:.:.|..:|.|  :.:...:..|.:..........||..|.:||.:......|.:.        
  Rat   620 LVDIQEDYLMWF--LHQSGMKARPSIMQDAVTLCSYPFIFDAQAKTKMLQTDAELQMQVAVNGAN 682

  Fly  1061 -------------YGQGPHKLKLHIRRSHLLEDAFRRIMSANKKDLQRGRLAVLWDTEEGLDYGG 1112
                         ..:.|. |.||:||:||:.||.|.:...:..||:: .|.|::|.|||:|.||
  Rat   683 LQNVFMLLTLEPLLARSPF-LVLHVRRNHLVGDALRELSIHSDIDLKK-PLKVIFDGEEGVDAGG 745

  Fly  1113 PSREFFFLLSRELFNPYYGLFEYSANDTYTVQVSPLSAFVDNC---HDWFRFSGRVLGLALVHQY 1174
            .::|||.||.:||.||.||:|.|       .|.|.|..|.|.|   |:||...|...|||:.:..
  Rat   746 VTKEFFLLLLKELLNPIYGMFTY-------YQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNST 803

  Fly  1175 LLDAFFTRPFYKALLRLPVALSDLESLDNEFHQSLQWIRDNDIGTGVDLGLTFC----VTEELLG 1235
            ::|..|....||.||.:..:|.||:.|.....:|||.:.|.   .|.|:..|||    |..|..|
  Rat   804 VVDLHFPLALYKKLLNVKPSLEDLKELSPTEGRSLQELLDY---PGEDIEETFCLNFTVCRESYG 865

  Fly  1236 SVVDRELKPGGKNIIINEKNKKEYLERMIKWRLERGVQEQTESLVRGFYEVIDSRLVSVFDAREL 1300
            .:..::|.|||..:.:.:.|::|:::..:.:..:..|.|...:...||.:|...:::.:|...||
  Rat   866 VIEQKKLIPGGDRVAVCKDNRQEFVDAYVNYIFQISVHEWYTAFSSGFLKVCGGKVLELFQPAEL 930

  Fly  1301 ELVIAGTAEIDTNDWRLNTEYRSGYHDNHQVIVWFWQVIERFSNEQRLRLLQFVTGTSSIPYEGF 1365
            ..::.|.:..:..:......|:..|...|..:..||:....|..|::.|.|.|:||:..||..|.
  Rat   931 RAMMVGNSNYNWEELEETAVYKGDYSSTHPTVKLFWETFHEFPLEKKKRFLLFLTGSDRIPIYGM 995

  Fly  1366 SALR-----GSTGPRRFCIEKWGKPNALPRAHTCFNRLDLPPYPTPELLYEKLLLAVEETNTFGI 1425
            ::|:     .:||           .:.||.||||:|.||||.|.:.|::..:|..|::....|.:
  Rat   996 ASLQIVIQSTATG-----------EDYLPVAHTCYNLLDLPKYSSKEIMKARLTQALDNYEGFSL 1049

  Fly  1426  1425
              Rat  1050  1049

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42797NP_572574.2 WW 638..667 CDD:278809
HECTc 1068..1424 CDD:238033 117/367 (32%)
HECTc 1092..1423 CDD:214523 107/342 (31%)
Herc3NP_001102101.1 ATS1 2..331 CDD:227511
RCC1 313..377 CDD:395335
HECTc 702..1048 CDD:238033 117/367 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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