DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42797 and Hectd3

DIOPT Version :9

Sequence 1:	NP_572574.2	Gene:	CG42797 / 31905	FlyBaseID:	FBgn0261931	Length:	1426	Species:	Drosophila melanogaster
Sequence 2:	XP_008762291.1	Gene:	Hectd3 / 313525	RGDID:	1309823	Length:	861	Species:	Rattus norvegicus

Alignment Length:	350	Identity:	90/350 - (25%)
Similarity:	155/350 - (44%)	Gaps:	67/350 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1102 WDTE---EG-LDYGGPSREFFFLLSRELFNPYYGLFEYSANDTYTVQVSPLSAFV---------- 1152
            |:.:   || :|.||..|:....:|.||..        |:.||..    ||..||
  Rat   528 WECKFIAEGIIDQGGGFRDSLADMSEELCP--------SSADTPV----PLPFFVRTANQGNGTG 580

  Fly  1153 ---------DNCHDWFRFS--GRVLGLALVHQYLLDAFFTRPFYKALLRLPVALS-DLESLDNEF 1205
                     .:|.|:.::.  |:::|.||..:..|........:|.|....|:.| |..::|:..
  Rat   581 EARDMYVPNPSCRDFAKYEWIGQLMGAALRGKEFLVLALPGFVWKQLSGEEVSWSKDFPAVDSVL 645

  Fly  1206 HQSLQWIRDNDIGT-----GVDLGLTFCVTEELLGSVVDRELKPGGKNIIINEKNKKEYLERMIK 1265
            .:.|:.:...|..|     |.:|..|..::::   .||  ||.|||..|::..:::..:::.:.|
  Rat   646 VKLLEVMEGVDKETFEFKFGKELTFTTVLSDQ---QVV--ELIPGGTGIVVGYEDRLRFIQLVQK 705

  Fly  1266 WRLERGVQEQTESLVRGFYEVIDSRLVSVFDARELELVIAGTAEIDTNDWRLNTEYRSGYHDNHQ 1330
            .|||.. :||..::..|..:|:...::.:...:|||..:.|..|:..:..|..|.:.. :..:..
  Rat   706 ARLEES-KEQVAAMQAGLLKVVPQAVLDLLTWQELEKKVCGDPEVTVDALRKLTRFED-FEPSDT 768

  Fly  1331 VIVWFWQVIERFSNEQRLRLLQFVTGTSSIPYEGFSALRGSTGPRRFCI--EKWG--KPNALPRA 1391
            .:.:||:.:..|:||.|.|.|:||||.|.:             |.|..|  :|.|  ..:|||.:
  Rat   769 RVQYFWEALNNFTNEDRSRFLRFVTGRSRL-------------PARIYIYPDKLGYETTDALPES 820

  Fly  1392 HTCFNRLDLPPYPTPELLYEKLLLA 1416
            .||.:.|.||.|.:.::..|||..|
  Rat   821 STCSSTLFLPHYASAKVCEEKLRYA 845

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42797	NP_572574.2	WW	638..667	CDD:278809
		HECTc	1068..1424	CDD:238033	89/349 (26%)
		HECTc	1092..1423	CDD:214523	89/349 (26%)
Hectd3	XP_008762291.1	APC10-HECTD3	238..371	CDD:176487
Hectd3	XP_008762291.1	HECT	579..845	CDD:395507	72/285 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900