Protein Alignment CG42797 and Wwc1

DIOPT Version :9

• Sequence 1: NP_572574.2
• Gene: CG42797 / 31905
• FlyBaseID: FBgn0261931
• Length: 1426
• Species: Drosophila melanogaster
• Sequence 2: XP_002727807.1
• Gene: Wwc1 / 303039
• RGDID: 1308329
• Length: 1108
• Species: Rattus norvegicus
• Alignment Length: 634
• Identity: 122/634 - (19%)
• Similarity: 181/634 - (28%)
• Gaps: 284/634 - (44%)

  Fly   635 EPPLPPAWEARMDSHGRIFYIDHTTRTTSWQRPGAAPSGGPAGREQHHRQQLDRRYQSIRRTITN 699
            |.|||..||...|..|:::||||..|||||..|
  Rat     5 ELPLPEGWEEARDFDGKVYYIDHRNRTTSWIDP-------------------------------- 37

  Fly   700 ESRAAQLYNLPTSANSNANSTAPAAPPPATAIHPAILMLCRPDFYSLLHTNEAALAIYNRNAALK 764
                                                                             
  Rat    38 ----------------------------------------------------------------- 37

  Fly   765 HMVMRIRRDPPCFQRYQYNKDLVALVNTFAQ-MSRELPSCWETKLDQSGKQFFIDHQHRRTSFMD 828
                          |.:|.|.|     |||. :|.|||..||...|.....:||||..:.|...|
  Rat    38 --------------RDRYTKPL-----TFADCISDELPLGWEEAYDPQVGDYFIDHNTKTTQIED 83

  Fly   829 PRL-----------------------PVECPRVVRHRQQHSQQQ--------------------- 849
            ||:                       ..|..:|.:.|.:.:||:
  Rat    84 PRVQWRREQEHMLKDYLVVAQEALSAQKEIYQVKQQRLELAQQEYQQLHAVWEHKLGSQVSLVSG 148

  Fly   850 -SSVGYYYPDLVDGNCLSATSG---------HINASPASSVSGVPPLP--PPRPSSSSSSSRSSH 902
             ||...|.|:::.....:|.|.         |:.........|...|.  ..|.|.:....:...
  Rat   149 SSSSSKYDPEILKAEIATAKSRVNKLKREMVHLQHELQFKERGFQTLKKIDERMSDAQGGYKLDE 213

  Fly   903 GHGHNCNTTS---AISC-----------------ALNADRSAYGAAGMASAGATAAGYEDVPIAY 947
            .......|.:   ||:|                 ....||.::.....:|:...::.: .||
  Rat   214 AQAVLRETKAIKKAITCGEKEKQDLIKSLAMLKDGFRTDRGSHSDLWSSSSSLESSSF-PVP--- 274

  Fly   948 NEKVIAFLRQPNILEILRERQGQH--TMSRQLREKINILRVEGVPALERLGHDLQLTILLSLFEQ 1010
             ::.:....|.:|       .|..  :.|.||.||:. ||:....|..|:.:   |.|.|:..:.
  Rat   275 -KQFLDVSSQTDI-------SGSFSTSSSNQLAEKVR-LRLRYEEAKRRIAN---LKIQLAKLDS 327

  Fly  1011 EIMGFVPIEER-------------------SP----QGSPVLNSRMPQRAPPPFRRDFEAKLRSF 1052
            |....|...||                   ||    ||. |....|.:|.   ..:|.:|.
  Rat   328 EAWPGVLDSERDRLILINEKEELLKEMRFISPRKWTQGE-VEQLEMARRR---LEKDLQAA---- 384

  Fly  1053 YRKLESKGYGQGPHKLKLHIRRSHL---LEDAFRRI---------MSANKKDL-----------Q 1094
             |..:||...:   :|||:.:|:.|   ||:|.|::         :|::.:.|           .
  Rat   385 -RDTQSKALTE---RLKLNSKRNQLVRELEEATRQVAALHSQLKSLSSSMQSLSSGSSPGSLTSS 445

  Fly  1095 RGRLA--------------VLWDTEEGLDYGGPSR-EFFFLLSRELFNP 1128
            ||.||              :.:|..|.||...||: |..||.....|.|
  Rat   446 RGSLAASSLDSSTSASFTDLYYDPFEQLDSELPSKVELLFLEGATGFRP 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42797	NP_572574.2	WW	638..667	CDD:278809	15/28 (54%)
		HECTc	1068..1424	CDD:238033	26/99 (26%)
		HECTc	1092..1423	CDD:214523	16/63 (25%)
Wwc1	XP_002727807.1	WW	9..39	CDD:238122	15/140 (11%)
		WW	55..84	CDD:278809	10/28 (36%)
		ALDH-SF	378..>420	CDD:299846	14/49 (29%)
		C2_Kibra	661..784	CDD:176062

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900