DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31957 and EIF1AD

DIOPT Version :9

Sequence 1:	NP_001260011.1	Gene:	CG31957 / 319046	FlyBaseID:	FBgn0051957	Length:	159	Species:	Drosophila melanogaster
Sequence 2:	NP_001229410.1	Gene:	EIF1AD / 84285	HGNCID:	28147	Length:	165	Species:	Homo sapiens

Alignment Length:	164	Identity:	71/164 - (43%)
Similarity:	110/164 - (67%)	Gaps:	20/164 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SRRKHLMKEMMEDDYALPTETQQIARVISSRGNNLHEVETVD-ETFLVSMPNKFRKSMWVKRGDF 72
            ::|||::||:: .::.:|::.|||.||:.:.|||||||||.. :.||||||:|:||::|:|||||
Human     5 TKRKHVVKEVL-GEHIVPSDQQQIVRVLRTPGNNLHEVETAQGQRFLVSMPSKYRKNIWIKRGDF 68

  Fly    73 LLVEPIEEGDKVKAEICKILTPEHIKEYTKAAIWPDKFTKKPVQEEATSQNK------------- 124
            |:|:|||||:||||||..:|..:|::...|...||:.|::  |.|:..::|:
Human    69 LIVDPIEEGEKVKAEISFVLCKDHVRSLQKEGFWPEAFSE--VAEKHNNRNRQTQPELPAEPQLS 131

  Fly   125 -DDSDFED--DLLPNTNRPVNRDSSDEEEDEETS 155
             ::|..||  ||..||||....:|.:|.|:||.:
Human   132 GEESSSEDDSDLFVNTNRRQYHESEEESEEEEAA 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31957	NP_001260011.1	S1_like	30..106	CDD:299122	45/76 (59%)
EIF1AD	NP_001229410.1	Nuclear localization signal. /evidence=ECO:0000255	6..12		3/5 (60%)
		S1_eIF1AD_like	25..102	CDD:240218	45/76 (59%)
		Nuclear localization signal. /evidence=ECO:0000255	56..65		4/8 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	112..165		15/52 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159973
Domainoid	1	1.000	90	1.000	Domainoid score	I7822
eggNOG	1	0.900	-	-		E1_KOG2925
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41860
Inparanoid	1	1.050	136	1.000	Inparanoid score	I4578
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55346
OrthoDB	1	1.010	-	-		D1431625at2759
OrthoFinder	1	1.000	-	-		FOG0004941
OrthoInspector	1	1.000	-	-		oto91217
orthoMCL	1	0.900	-	-		OOG6_104365
Panther	1	1.100	-	-	LDO	PTHR21641
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4030
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.770