Protein Alignment LysRS and lysU

DIOPT Version :9

• Sequence 1: NP_001188571.1
• Gene: LysRS / 31904
• FlyBaseID: FBgn0027084
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_418553.1
• Gene: lysU / 948645
• ECOCYCID: EG10553
• Length: 505
• Species: Escherichia coli
• Alignment Length: 523
• Identity: 217/523 - (41%)
• Similarity: 320/523 - (61%)
• Gaps: 26/523 - (4%)

  Fly    75 KKSSAAEEEEISPNEYFKLRSAAVQELKRSPATDPYPHKF---HVSSSL-EDFIAKYENSLKEGE 135
            ::.:....|.|..|:..:.|...:..|::....  :|:.|   |.|..| |:|.||....|   |
E. coli     3 EQETRGANEAIDFNDELRNRREKLAALRQQGVA--FPNDFRRDHTSDQLHEEFDAKDNQEL---E 62

  Fly   136 TLENVKLSVAGRVHAIRESGAKLIFYDLRGEGVKVQVMASAKSYKSEADFEIDTSKLRRGDIIGV 200
            :| |:::|||||:...|..| |..|..|:..|.::|:.. |:....|..:.....|...|||||.
E. coli    63 SL-NIEVSVAGRMMTRRIMG-KASFVTLQDVGGRIQLYV-ARDSLPEGVYNDQFKKWDLGDIIGA 124

  Fly   201 VGHPGKTKKGELSVMPSEIKLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNNNVREKFQIRAK 265
            .|...||:.||||:..:|::||:..|..||....||:|:|.||||||||||.|:..|:.|.:|:|
E. coli   125 RGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSK 189

  Fly   266 IISYVRQFLDRLGFLEIETPMMNMIAGGATAKPFVTHHNDLKMDLFMRIAPELYHKMLVVGGLDR 330
            |::.:|||:...||:|:|||||.:|.|||:|:||:||||.|.:|:::|||||||.|.|||||.:|
E. coli   190 ILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFER 254

  Fly   331 VYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYADIMDITEQLVSGMVKAIRGSYKVIYHPEGPE 395
            |:||.|.||||||.:.||||||..|.|||||||.|::::||.|...:.:.:.|:.||.|
E. coli   255 VFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTY------ 313

  Fly   396 GPEQELDFTPPFKRVSMIKTLEE-KLQVKFPAADTFNSPETNQFLSQLCAKHQVECPAPRTTARL 459
             .|...||..||::::|.:.::: :.:......|.|::.:.      |.....:.........|:
E. coli   314 -GEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKA------LAESIGITVEKSWGLGRI 371

  Fly   460 LDKLVGEFIEEFCVNPTFICEHPQIMSPLAKYHRSIPGLTERFELFVAKKEICNAYTELNDPVVQ 524
            :.::..|..|...:.||||.|:|..:||||:.:...|.:|:|||.|:..:||.|.::||||...|
E. coli   372 VTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQ 436

  Fly   525 RERFEQQASDKAAGDDEAQLVDENFCTSLEYGLPPTGGFGMGIDRLAMFLTDSNNIKEVLLFPAM 589
            .|||::|.:.||||||||...||::.|:||||||||.|.|:||||:.|..|:|:.|::|:|||||
E. coli   437 AERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAM 501

  Fly   590 KPE 592
            :|:
E. coli   502 RPQ 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LysRS	NP_001188571.1	PLN02502	42..593	CDD:215278	217/523 (41%)
		LysRS_N	141..250	CDD:239817	44/108 (41%)
		LysRS_core	253..591	CDD:238398	151/338 (45%)
lysU	NP_418553.1	PRK12445	1..505	CDD:171504	217/523 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	320	1.000	Domainoid score	I30
eggNOG	1	0.900	-	-		E1_COG1190
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	381	1.000	Inparanoid score	I54
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002656
OrthoInspector	1	1.000	-	-		otm51363
orthoMCL	1	0.900	-	-		OOG6_100559
Panther	1	1.100	-	-	O	PTHR42918
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1764
SwiftOrtho	1	1.000	-	-
	10	9.860