Protein Alignment LysRS and DED81

DIOPT Version :9

• Sequence 1: NP_001188571.1
• Gene: LysRS / 31904
• FlyBaseID: FBgn0027084
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_011883.1
• Gene: DED81 / 856412
• SGDID: S000001061
• Length: 554
• Species: Saccharomyces cerevisiae
• Alignment Length: 591
• Identity: 122/591 - (20%)
• Similarity: 219/591 - (37%)
• Gaps: 153/591 - (25%)

  Fly    72 AGKKKSSAAEEE----EISPNEYFKLRSAAV-------------------QELKRSPATDPYPHK 113
            |.::||.|.|.:    :...|||.::.::|:                   ||||:....
Yeast    34 ASQQKSDATEPKLFVFKTEDNEYQEISASALKKARKGCDGLKKKAVKQKEQELKKQQKE------ 92

  Fly   114 FHVSSSLEDFIAKYENSLKEGETLE--------------NVKLSVAGRVHAIRESGAKLIFYDLR 164
               :.:....::....::||.|:|.              ..::.|:|.:|.:| |..|:||..||
Yeast    93 ---AENAAKQLSALNITIKEDESLPAAIKTRIYDSYSKVGQRVKVSGWIHRLR-SNKKVIFVVLR 153

  Fly   165 -GEGVKVQVMASAKSYKSEA-DFEIDTSKLRRGDIIGVVGHPGKTKKG--ELSVMPSEIKLLSPC 225
             |.|....|::...:...:. |..::::....|.|:.:  ..|||..|  ||:|...|:..|:|
Yeast   154 DGSGFIQCVLSGDLALAQQTLDLTLESTVTLYGTIVKL--PEGKTAPGGVELNVDYYEVVGLAP- 215

  Fly   226 LHMLPHLHFGLKDKETR-----------YRQRYLDLILNNNVREKFQIRAKIISYVRQFLDRLGF 279
                     |.:|..|.           ..||:|.| ..:.:....::||.::..||:..|....
Yeast   216 ---------GGEDSFTNKIAEGSDPSLLLDQRHLAL-RGDALSAVMKVRAALLKSVRRVYDEEHL 270

  Fly   280 LEIETPMM--NMIAGGATAKPFVTHHNDLKM-----DLFMRIAPELYHKMLVVGGLDRVYEIGRQ 337
            .|:..|.|  ..:.||:|.         .||     :.::..:.:||.: ..:..|..||.|...
Yeast   271 TEVTPPCMVQTQVEGGSTL---------FKMNYYGEEAYLTQSSQLYLE-TCLASLGDVYTIQES 325

  Fly   338 FRNE-GIDLTHNPEFTTCEFYMAYADYADIMDITEQLV-------------SGMVKAIRGSYKVI 388
            ||.| .....|..|:|..|..:|:..:.|::...|.|:             ..:||.:..::|
Yeast   326 FRAEKSHTRRHLSEYTHIEAELAFLTFDDLLQHIETLIVKSVQYVLEDPIAGPLVKQLNPNFK-- 388

  Fly   389 YHPEGPEGPEQELDFTPPFKRVSMIKTLEEKLQVKFPAADTFNSPETNQFLSQLCAKHQVECPAP 453
                .|:.|...|.:.      ..|..|.|. .:|....:.|      :|...:.
Yeast   389 ----APKAPFMRLQYK------DAITWLNEH-DIKNEEGEDF------KFGDDIA---------- 426

  Fly   454 RTTARLLDKLVGEFIEEFCVNPTFICEHP-QIMSPLAKYHRSIPGLTERFELFVAK-KEICNAYT 516
            ....|.:...:|.        |.|:...| :|.|...|.....|.:||..::.:.. .||.....
Yeast   427 EAAERKMTDTIGV--------PIFLTRFPVEIKSFYMKRCSDDPRVTESVDVLMPNVGEITGGSM 483

  Fly   517 ELNDPVVQRERFEQQASDKAAGDDEAQLVDENFCTSLEYGLPPTGGFGMGIDRLAMFLTDSNNIK 581
            .::|.......|:::..|.   |.....:|:.     :||..|.||:|:|.:|:..:|.|...::
Yeast   484 RIDDMDELMAGFKREGIDT---DAYYWFIDQR-----KYGTCPHGGYGIGTERILAWLCDRFTVR 540

  Fly   582 EVLLFP 587
            :..|:|
Yeast   541 DCSLYP 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LysRS	NP_001188571.1	PLN02502	42..593	CDD:215278	122/591 (21%)
		LysRS_N	141..250	CDD:239817	32/123 (26%)
		LysRS_core	253..591	CDD:238398	72/358 (20%)
DED81	NP_011883.1	AsnS	116..554	CDD:223096	105/500 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910