Protein Alignment LysRS and DPS1

DIOPT Version :9

• Sequence 1: NP_001188571.1
• Gene: LysRS / 31904
• FlyBaseID: FBgn0027084
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_013083.1
• Gene: DPS1 / 850643
• SGDID: S000003941
• Length: 557
• Species: Saccharomyces cerevisiae
• Alignment Length: 596
• Identity: 148/596 - (24%)
• Similarity: 246/596 - (41%)
• Gaps: 126/596 - (21%)

  Fly    42 TKLELKRRLKAEQKAKEKAEKAAAAPAENTAGKKKSSAAEEEEISPNEYFKLRSAAVQELKRSPA 106
            :|..||:..|.::|.::|.|:|....||..|.:||::|   |:.:.:.|.||   .:.:.:.|..
Yeast    30 SKKALKKLQKEQEKQRKKEERALQLEAEREAREKKAAA---EDTAKDNYGKL---PLIQSRDSDR 88

  Fly   107 TDPYPHKFHVSSSLEDFIAKYENSLKEGETLENVKLSVAGRVHAIRESGAKLIFYDLRGEGVKVQ 171
            |.....||......:|       |.||        :....|||..|:.||.|.|..||.:...:|
Yeast    89 TGQKRVKFVDLDEAKD-------SDKE--------VLFRARVHNTRQQGATLAFLTLRQQASLIQ 138

  Fly   172 VMASAKS--------YKSEADFEIDTSKLRRGDIIGVVGHPGKTKKGE-LSVMPSEIKLLSPCLH 227
            .:..|..        .|......:::..|.|| |:..|..|.|:...: |.:..::|..:|....
Yeast   139 GLVKANKEGTISKNMVKWAGSLNLESIVLVRG-IVKKVDEPIKSATVQNLEIHITKIYTISETPE 202

  Fly   228 MLPHLHFGLKDK-----------------ETRYRQRYLDL--ILNNNVREKFQIRAKIISYVRQF 273
            .||.|   |:|.                 :||...|.:||  :.|..:   |:|:|.:....|::
Yeast   203 ALPIL---LEDASRSEAEAEAAGLPVVNLDTRLDYRVIDLRTVTNQAI---FRIQAGVCELFREY 261

  Fly   274 LDRLGFLEIETP-MMNMIAGGATAKPFVTHHNDLKMDLFMRIAPELYHKMLVVGGLDRVYEIGRQ 337
            |....|.|:.|| ::...:.|.::...||:   .|...::..:|:...:.|:|...:||||||..
Yeast   262 LATKKFTEVHTPKLLGAPSEGGSSVFEVTY---FKGKAYLAQSPQFNKQQLIVADFERVYEIGPV 323

  Fly   338 FRNEGIDL-THNPEFTTCEFYMAYAD-YADIMDITEQL-----------VSGMVKAIRGSYKVIY 389
            ||.|..:. .|..|||..:..||:.: |.:::|...:|           .:..::.:|..|
Yeast   324 FRAENSNTHRHMTEFTGLDMEMAFEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQY---- 384

  Fly   390 HPEGPEGPEQELDFTPPFKRVSMIKTLEEKLQVKFPAADTFN-----SPETNQFLSQLCA-KHQV 448
                   |.:|.......|.|.:  |.:|.:::...|.....     |.|..:||.:|.. |:.
Yeast   385 -------PVEEFKLPKDGKMVRL--TYKEGIEMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYD- 439

  Fly   449 ECPAPRTTARLLDKLVGEFIEEFCVNPTFICEHPQIMSPLAKYHRSIPGLTERFELFVAKKEICN 513
                  |...:|||...|      :.|.:....|  .:|  ||..|       ::.|:..:||.:
Yeast   440 ------TDFYILDKFPLE------IRPFYTMPDP--ANP--KYSNS-------YDFFMRGEEILS 481

  Fly   514 AYTELNDPVVQRERFEQQASDKAAG--DDEAQLVDENFCTSLEYGLPPTGGFGMGIDRLAMFLTD 576
            ....::|..:.:||.      ||.|  .::..|.|  :|....||.||..|.|:|::|:.||..|
Yeast   482 GAQRIHDHALLQERM------KAHGLSPEDPGLKD--YCDGFSYGCPPHAGGGIGLERVVMFYLD 538

  Fly   577 SNNIKEVLLFP 587
            ..||:...|||
Yeast   539 LKNIRRASLFP 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LysRS	NP_001188571.1	PLN02502	42..593	CDD:215278	148/596 (25%)
		LysRS_N	141..250	CDD:239817	31/134 (23%)
		LysRS_core	253..591	CDD:238398	89/357 (25%)
DPS1	NP_013083.1	PLN02850	19..557	CDD:215456	148/596 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910