DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment LysRS and NS1

DIOPT Version :9

Sequence 1:NP_001188571.1 Gene:LysRS / 31904 FlyBaseID:FBgn0027084 Length:607 Species:Drosophila melanogaster
Sequence 2:NP_001328216.1 Gene:NS1 / 827443 AraportID:AT4G17300 Length:587 Species:Arabidopsis thaliana


Alignment Length:568 Identity:113/568 - (19%)
Similarity:203/568 - (35%) Gaps:171/568 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   108 DPYPHKFHVSSSLEDF-----IAKYENSLKEGETLENVKLSVAGRVHAIRESGAKLIFYDLRGEG 167
            :.|..:|  .|.:.:|     ||:.:....||.:.....|::.|.|..:| |.:.:.|.:: .:|
plant    95 ESYEKRF--GSKVGEFRKKLRIAEVKGGADEGLSRVGQSLNIMGWVRTLR-SQSSVTFIEI-NDG 155

  Fly   168 VKVQVMASAKSYKSEADFEIDTSKLRRGDIIGV----VGHPGKTKKGELSVMPSEIKLLSPCLHM 228
            ..:..:....:..:|...::::..:..|..:.|    |...|..:|.||.|  .:|.::..|...
plant   156 SCLSNLQCVMTSDAEGYDQVESGSILTGASVSVQGTIVASQGTKQKVELKV--EKIIVVGECDSS 218

  Fly   229 LPHLHFGLKDKETRYRQRYLDLILNNNVREKFQIRAK-----IISYVR--------QFLDRLGFL 280
            .|       .::.|..:.:|        |.|..:|.:     .::.||        :|....||:
plant   219 YP-------IQKKRVSREFL--------RTKAHLRPRTNTFGAVARVRNTLAYATHKFFQESGFV 268

  Fly   281 EIETPMMNMI-AGGATAKPFVT------HHN----------------DLKMDLFMRIAPELYHKM 322
            .:.:|::... ..||..:..||      |.|                |...|.|.:.|      .
plant   269 WVASPIITASDCEGAGEQFCVTTLIPSSHENTDTSIDAIPKTKGGLIDWSQDFFGKPA------F 327

  Fly   323 LVVGG----------LDRVYEIGRQFRNEGIDLT-HNPEFTTCEFYMAYADYADIMDITEQLVSG 376
            |.|.|          |..||..|..||.|..:.: |..||...|..:|:||..|.|......:..
plant   328 LTVSGQLNGETYATALSDVYTFGPTFRAENSNTSRHLAEFWMIEPELAFADLDDDMACATAYLQY 392

  Fly   377 MVKAIRGSYKVIYHPEGPEGPEQELDFTPPFKRVSMIKTLE-------------EKLQVKFPAAD 428
            :||.:..:.|            ::::|...:....:|:.|.             :.:::...|..
plant   393 VVKYVLDNCK------------EDMEFFDTWIEKGIIRRLSDVAEKEFLQLGYTDAIEILLKANK 445

  Fly   429 TFNSPETNQFLSQLCAKHQVECPAPRTTARLLDKLVGEFIEEFCVNPTFICEHPQIMSPLAKYHR 493
            .|:.|.  ::...|.::|              ::.:.|  |.|...|..|.::|           
plant   446 KFDFPV--KWGLDLQSEH--------------ERYITE--EAFGGRPVIIRDYP----------- 481

  Fly   494 SIPGLTERFELFVAKKEICNAYTELND----------------PVVQRERFEQQASDKAAGDDEA 542
                           |||...|...||                .::...:.|::.....|..||.
plant   482 ---------------KEIKAFYMRENDDGKTVAAMDMLVPRIGELIGGSQREERLEVLEARLDEL 531

  Fly   543 QLVDENFCTSLE---YGLPPTGGFGMGIDRLAMFLTDSNNIKEVLLFP 587
            :|..|::...|:   ||..|..|||:|.:||..|:|..:||::|:.||
plant   532 KLNKESYWWYLDLRRYGSVPHAGFGLGFERLVQFVTGIDNIRDVIPFP 579

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LysRSNP_001188571.1 PLN02502 42..593 CDD:215278 113/568 (20%)
LysRS_N 141..250 CDD:239817 21/112 (19%)
LysRS_core 253..591 CDD:238398 84/414 (20%)
NS1NP_001328216.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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