DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LysRS and OVA5

DIOPT Version :9

Sequence 1:	NP_001188571.1	Gene:	LysRS / 31904	FlyBaseID:	FBgn0027084	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	NP_187958.1	Gene:	OVA5 / 820551	AraportID:	AT3G13490	Length:	602	Species:	Arabidopsis thaliana

Alignment Length:	594	Identity:	226/594 - (38%)
Similarity:	324/594 - (54%)	Gaps:	58/594 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 SKQTKL----------ELKRRLKAEQKAKEKAEKAAAAPAENTAGKKKSSAAEEEEISPNEYFK- 92
            |..|:|          .|...|:....|...:..|..|.....:|:.:.||:.....|..|..:
plant    22 SSSTRLATTIYGRRSYHLSPALRCASAASSSSSSATTAETSKPSGRNRRSASSSNSTSDREAIRS 86

  Fly    93 LRSAAVQELKRSPATDPYPHKFHVSSSLEDFIAKYENSLKEGETLENV--KLSVAGRVHAIRESG 155
            :|...|:|| |....:||.:|:..|.|.......|:: |..||..:|.  .:|:||||.|.|..|
plant    87 IRLKKVEEL-RGQGLEPYAYKWEKSHSANQLQEIYKH-LANGEESDNEIDCVSIAGRVVARRAFG 149

  Fly   156 AKLIFYDLRGEGVKVQVMASAKSYKSEADFEIDTSKLRRGDIIGVVGHPGKTKKGELSVMPSEIK 220
             ||.|..||.:...:|:... |...|:..||.....:..|||:|..|...:|:|||||:..:...
plant   150 -KLAFLTLRDDSGTIQLYCE-KERLSDDQFEQLKQFIDIGDILGASGSMKRTEKGELSICVNSFS 212

  Fly   221 LLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNNNVREKFQIRAKIISYVRQFLDRLGFLEIETP 285
            :|:..|..||..:.||.|.:.||||||:|:|.|..|.:.|:.||||:|.:|:.::..|:||:|||
plant   213 ILTKSLLPLPDKYHGLTDIDKRYRQRYVDMIANPEVADVFRRRAKIVSEIRKTVESFGYLEVETP 277

  Fly   286 MMNMIAGGATAKPFVTHHNDLKMDLFMRIAPELYHKMLVVGGLDRVYEIGRQFRNEGIDLTHNPE 350
            ::...||||.|:||||.||.|..||::|||.||:.|.::|||.::||||||.||||||...||||
plant   278 VLQGAAGGAEARPFVTFHNSLGRDLYLRIATELHLKRMLVGGFEKVYEIGRIFRNEGISTRHNPE 342

  Fly   351 FTTCEFYMAYADYADIMDITEQLVSGMVKAIRGSYKVIYHPEGPEGPEQELDFTPPFKRVSMIKT 415
            |||.|.|.||:||..:||:.|.:|:....|:.|...:.|     :|.|..|:  .|::|.:|...
plant   343 FTTIEMYEAYSDYHSMMDMAELIVTQCSMAVNGKLTIDY-----QGTEICLE--RPWRRETMHNL 400

  Fly   416 LEEKLQVKFP--AADTFNSPETNQFLSQLCAKHQVECPAPRTTAR-------LLDKLVGEFIEEF 471
            ::|...:.|.  ..|..|:.:|     .|.|...|..|..::..|       ||:::....:|..
plant   401 VKEITGINFSELGEDLGNAKDT-----VLLALQDVLEPKDKSGIRACSSLGHLLNEIFEVVVEPK 460

  Fly   472 CVNPTFICEHPQIMSPLAKYHRSIPGLTERFELFVAKKEICNAYTELNDPVVQRERFEQQA---- 532
            .|.|||:.::|..:|||||.||...|||||||||:..:|:.||::||.|||.||.|.|:|.
plant   461 LVQPTFVLDYPIEISPLAKPHRGNAGLTERFELFICGREMANAFSELTDPVDQRTRLEEQVRQHN 525

  Fly   533 --------------SDKAAGDDEAQLV--DENFCTSLEYGLPPTGGFGMGIDRLAMFLTDSNNIK 581
                          :.|...|||:..|  ||:|.|:||||:||..|.|:|||||.|.||:|.:|:
plant   526 AKRAEAVRESPEPNAKKDDDDDESYEVTLDEDFLTALEYGMPPASGMGLGIDRLVMLLTNSASIR 590

  Fly   582 EVLLFPAMK 590
            :|:.||.:|
plant   591 DVIAFPVLK 599

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LysRS	NP_001188571.1	PLN02502	42..593	CDD:215278	225/591 (38%)
		LysRS_N	141..250	CDD:239817	42/108 (39%)
		LysRS_core	253..591	CDD:238398	154/367 (42%)
OVA5	NP_187958.1	PLN02502	80..602	CDD:215278	214/536 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53889
OrthoDB	1	1.010	-	-		D837479at2759
OrthoFinder	1	1.000	-	-		FOG0002656
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100559
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1764
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.690