Protein Alignment LysRS and Nars

DIOPT Version :9

• Sequence 1: NP_001188571.1
• Gene: LysRS / 31904
• FlyBaseID: FBgn0027084
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_001363950.1
• Gene: Nars / 70223
• MGIID: 1917473
• Length: 549
• Species: Mus musculus
• Alignment Length: 605
• Identity: 133/605 - (21%)
• Similarity: 226/605 - (37%)
• Gaps: 170/605 - (28%)

  Fly    31 VSAPQMEPSKQTKLELKRRLKAEQKAKEKAEKAAAAPAENTAGKKKSSAAEEEEISPNEYFKLRS 95
            :|..||:..|  |:..:.::|.:.:.|::||       :|.  :::.:..|.::|.
Mouse    59 ISKSQMKNIK--KMWHREQMKNDSREKKEAE-------DNL--RREKNLEEAKKII--------- 103

  Fly    96 AAVQELKRSPATDPYPHKFHVSSSLEDFIAKYENSLKEGETLENVKLSVAGRVHAIRESGAKLIF 160
                 :|..|:. |.|             |..:.|..||...:.||  |.|.||.:|..|..|:|
Mouse   104 -----IKNDPSL-PEP-------------ACVKISALEGYRGQRVK--VFGWVHRLRRQGKNLMF 147

  Fly   161 YDLR-GEGVKVQVMASAKSYKSEADFEIDTSKLRRGDI------IGVVGHPGKTKKG-------E 211
            ..|| |.|....|::.            |..:...|.:      :.|.|....|.||       |
Mouse   148 LVLRDGTGYLQCVLSD------------DLCQCYNGVVLSTESSVAVYGTLNLTPKGKQAPGGHE 200

  Fly   212 LSVMPSEIKLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNNNVREKFQIRAKIISYVR-QFLD 275
            ||....|:..|:|. ....:|.....|.:.:...|:: :|...|:.:..:.|:.|....| .|.|
Mouse   201 LSCDFWELVGLAPA-GGADNLINEESDVDVQLNNRHM-MIRGENMSKILKARSMITRCFRDHFFD 263

  Fly   276 RLGFLEIETP--MMNMIAGGATAKPFVTHHNDLKMD-----LFMRIAPELYHKMLVVGGLDRVYE 333
            | |:.|:.||  :...:.||||.         .|:|     .|:..:.:||.: ..:..|..|:.
Mouse   264 R-GYCEVTTPTLVQTQVEGGATL---------FKLDYFGEEAFLTQSSQLYLE-TCLPALGDVFC 317

  Fly   334 IGRQFRNE-GIDLTHNPEFTTCEFYMAYADYADIMDITEQLVSGMVKAIRGS--YKVIYHPEGPE 395
            |.:.:|.| .....|..|||..|....:..:.|:::..|.||..:|..:..|  ..::|
Mouse   318 IAQSYRAEQSRTRRHLAEFTHVEAECPFLTFEDLLNRLEDLVCDVVDRVLKSPVASIVY------ 376

  Fly   396 GPEQELDFTP---PFKRVSMIKTLE--EKLQVKFPAADTFNSPETNQFLSQLCAKHQVECPAPRT 455
              |...:|.|   ||:|::....:|  ::..||         .|...|       ::.....|..
Mouse   377 --ELNPNFKPPKRPFRRMNYSDAIEWLKEHDVK---------KEDGTF-------YEFGDDIPEA 423

  Fly   456 TARLLDKLVGEFIEEFCVNPTFICEHP-QIMSPLAKYHRSIPGLTERFELFVA------------ 507
            ..||:...:.|        |..:|..| :|.|...:.....|.|||..::.:.
Mouse   424 PERLMTDTINE--------PILLCRFPVEIKSFYMQRCPEDPRLTESVDVLMPNVGEIVGGSMRS 480

  Fly   508 --KKEICNAYTELNDPVVQRERFEQQASDKAAGDDEAQ---LVDENFCTSLEYGLPPTGGFGMGI 567
              .:||...|                   |..|.|.|.   ..|:.     :||..|.||:|:|:
Mouse   481 WDSEEILEGY-------------------KREGIDPAPYYWYTDQR-----KYGTCPHGGYGLGL 521

  Fly   568 DRLAMFLTDSNNIKEVLLFP 587
            :|...::.:..:|::|.|:|
Mouse   522 ERFLSWILNRYHIRDVCLYP 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LysRS	NP_001188571.1	PLN02502	42..593	CDD:215278	129/594 (22%)
		LysRS_N	141..250	CDD:239817	30/122 (25%)
		LysRS_core	253..591	CDD:238398	81/369 (22%)
Nars	NP_001363950.1	AsnS	126..549	CDD:223096	113/499 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910